Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction. - Wikidata - wikimedia - TriplyDB

Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction.

Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction.

http://www.wikidata.org/entity/Q34068556

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Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis Synaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon Synapses Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release The functional significance of synaptotagmin diversity in neuroendocrine secretion The calcium sensor synaptotagmin 7 is required for synaptic facilitation Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment Different types of retinal inhibition have distinct neurotransmitter release properties.Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy Vesicles derived via AP-3-dependent recycling contribute to asynchronous release and influence information transfer Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23 Altered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravis Zebrafish CaV2.1 calcium channels are tailored for fast synchronous neuromuscular transmission.A sequential vesicle pool model with a single release sensor and a Ca(2+)-dependent priming catalyst effectively explains Ca(2+)-dependent properties of neurosecretion.Transmembrane tethering of synaptotagmin to synaptic vesicles controls multiple modes of neurotransmitter release Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.Molecular underpinnings of synaptic vesicle pool heterogeneity.A Phenomenological Synapse Model for Asynchronous Neurotransmitter Release.Slow changes in Ca2(+) cause prolonged release from GABAergic retinal amacrine cells.N-terminal domain of complexin independently activates calcium-triggered fusion.Fatigue in Rapsyn-Deficient Zebrafish Reflects Defective Transmitter Release Synchronous and asynchronous modes of synaptic transmission utilize different calcium sources.Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release.Exocytosis and synaptic vesicle function.The molecular machinery of neurotransmitter release (Nobel lecture).Translating neuronal activity at the synapse: presynaptic calcium sensors in short-term plasticity.Molecular mechanisms governing Ca(2+) regulation of evoked and spontaneous release.Functionally heterogeneous synaptic vesicle pools support diverse synaptic signalling.C2-domain containing calcium sensors in neuroendocrine secretion.Synaptic Vesicle-Recycling Machinery Components as Potential Therapeutic Targets.The Mechanisms and Functions of Synaptic Facilitation.Zebrafish calls for reinterpretation for the roles of P/Q calcium channels in neuromuscular transmission.Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels.A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion.Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP.Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse.Heterogeneity of presynaptic proteins: do not forget isoforms.A Gradient in Synaptic Strength and Plasticity among Motoneurons Provides a Peripheral Mechanism for Locomotor Control.The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN.

P2860

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P2860

Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction.

http://www.wikidata.org/entity/Q34068556

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Distinct roles for two synapto ...... rafish neuromuscular junction.

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Distinct roles for two synapto ...... rafish neuromuscular junction.

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Distinct roles for two synapto ...... rafish neuromuscular junction.

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type

label

Distinct roles for two synapto ...... rafish neuromuscular junction.

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Distinct roles for two synapto ...... rafish neuromuscular junction.

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Distinct roles for two synapto ...... rafish neuromuscular junction.

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prefLabel

Distinct roles for two synapto ...... rafish neuromuscular junction.

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Distinct roles for two synapto ...... rafish neuromuscular junction.

@en

Distinct roles for two synapto ...... rafish neuromuscular junction.

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Proceedings of the National Academy of Sciences of the United States of America

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Distinct roles for two synapto ...... rafish neuromuscular junction.

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P2093

Gail Mandel

http://www.w3.org/2001/XMLSchema#string

Glen M Corson

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Hua Wen

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Matthew J McGinley

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Michael W Linhoff

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Paul Brehm

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P2860

Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release

A dual-Ca2+-sensor model for neurotransmitter release in a central synapse

Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas

Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells

Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis

Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release

Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities

Alternative splicing of synaptotagmins involving transmembrane exon skipping

Short-term synaptic plasticity

Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses

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13906-13911

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10.1073/PNAS.1008598107

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31

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107

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2010-07-19T00:00:00Z

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45275100

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20643933

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synchronous neurotransmitter secretion

asynchronous neurotransmitter secretion

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2922265

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