Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.
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The mitotic spindle: linking teratogenic effects of Zika virus with human genetics?Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1pThe E7 oncoprotein of human papillomavirus type 16 stabilizes p53 through a mechanism independent of p19(ARF).Productive replication of adeno-associated virus can occur in human papillomavirus type 16 (HPV-16) episome-containing keratinocytes and is augmented by the HPV-16 E2 protein.Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.Expression of the HPV18/E6 oncoprotein induces DNA damage.Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model.Compromised spindle assembly checkpoint due to altered expression of Ubch10 and Cdc20 in human papillomavirus type 16 E6- and E7-expressing keratinocytesGenomic instability and cancer: lessons learned from human papillomaviruses.Genomic Instability Induced By Human Papillomavirus Oncogenes.Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer.Multinucleation of koilocytes is in fact multilobation and is related to aberration of the G2 checkpointGenomic instability of the host cell induced by the human papillomavirus replication machineryMechanisms of human papillomavirus-induced oncogenesis.The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2Molecular mechanisms of human papillomavirus-induced carcinogenesis.pRB plays an essential role in cell cycle arrest induced by DNA damageBasal keratinocyte tetrasomy in low-grade squamous intra-epithelial lesions of the cervix is restricted to high and intermediate risk HPV infection but is not type-specificInduction of tetrasomy by human papillomavirus type 16 E7 protein is independent of pRb binding and disruption of differentiation.Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesDelocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitosesAbrogation of the postmitotic checkpoint contributes to polyploidization in human papillomavirus E7-expressing cells.E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte culturesHypoxia-specific stabilization of HIF-1alpha by human papillomavirusesThe papillomavirus E7 proteins.The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle.Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation.The human papillomavirus E7 oncoprotein as a regulator of transcription.Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint.The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle.Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites.Overexpression of simian virus 40 small-T antigen blocks centrosome function and mitotic progression in human fibroblasts.Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes.Alternative fates of keratinocytes transduced by human papillomavirus type 18 E7 during squamous differentiation.Modulation of the cell division cycle by human papillomavirus type 18 E4.Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1.Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein.Regulation of the human papillomavirus type 18 E6/E6AP ubiquitin ligase complex by the HECT domain-containing protein EDD.Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation.
P2860
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P2860
Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@ast
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@en
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@nl
type
label
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@ast
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@en
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@nl
prefLabel
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@ast
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@en
Human papillomavirus oncoprote ...... he mitotic spindle checkpoint.
@nl
P2860
P1433
P1476
Human papillomavirus oncoprote ...... the mitotic spindle checkpoint
@en
P2093
J T Thomas
L A Laimins
P2860
P304
P407
P577
1998-02-01T00:00:00Z