Circulating neprilysin clears brain amyloid - Wikidata - wikimedia - TriplyDB

Circulating neprilysin clears brain amyloid

Circulating neprilysin clears brain amyloid

http://www.wikidata.org/entity/Q34071954

about

The Alzheimer's amyloid-degrading peptidase, neprilysin: can we control it?Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders Biomarkers in amyloid-β immunotherapy trials in Alzheimer's disease.Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling.Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease.Transgenerational latent early-life associated regulation unites environment and genetics across generations Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease.Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease?Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease.Amyloid beta accumulation in HIV-1-infected brain: The role of the blood brain barrier Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?Clearance of amyloid-beta in Alzheimer's disease: shifting the action site from center to periphery.Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer's disease.Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).Neprilysin gene transfer: A promising therapeutic approach for Alzheimer's disease.Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.First-in-Class Composite Angiotensin Receptor-Neprilysin Inhibitors (ARNI) in Practice.Aβ-Degrading Proteases: Therapeutic Potential in Alzheimer Disease.Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques.The Role of Neprilysin Inhibitors in Cardiovascular Disease.A syringe-focused ultrasound device for simultaneous injection of DNA and gene transfer.Association Between Serum Amyloid-Beta and Renal Functions: Implications for Roles of Kidney in Amyloid-Beta Clearance.Sacubitril/Valsartan (LCZ696) in Heart Failure

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Circulating neprilysin clears brain amyloid

http://www.wikidata.org/entity/Q34071954

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Circulating neprilysin clears brain amyloid

@ast

Circulating neprilysin clears brain amyloid

@en

Circulating neprilysin clears brain amyloid

@nl

type

label

Circulating neprilysin clears brain amyloid

@ast

Circulating neprilysin clears brain amyloid

@en

Circulating neprilysin clears brain amyloid

@nl

prefLabel

Circulating neprilysin clears brain amyloid

@ast

Circulating neprilysin clears brain amyloid

@en

Circulating neprilysin clears brain amyloid

@nl

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J.MCN.2010.05.014

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Molecular and Cellular Neuroscience

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Circulating neprilysin clears brain amyloid

@en

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Christa Studzinski

http://www.w3.org/2001/XMLSchema#string

Louis B Hersh

http://www.w3.org/2001/XMLSchema#string

M Paul Murphy

http://www.w3.org/2001/XMLSchema#string

Ronald L Klein

http://www.w3.org/2001/XMLSchema#string

Tina Beckett

http://www.w3.org/2001/XMLSchema#string

Yinxing Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Clearance of amyloid-beta by circulating lipoprotein receptors

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice

Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease.

Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease

Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer's transgenic mice.

Mutation of active site residues of the puromycin-sensitive aminopeptidase: conversion of the enzyme into a catalytically inactive binding protein.

Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system.

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101-107

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scholarly article

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10.1016/J.MCN.2010.05.014

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2

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45

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44683039

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20558294

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2923273

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