MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionMass spectrometry imaging of therapeutics from animal models to three-dimensional cell culturesDiagnosis of inflammatory bowel disease: Potential role of molecular biometrics.Future technology insight: mass spectrometry imaging as a tool in drug research and development.A MALDI-MSI Approach to the Characterization of Radiation-Induced Lung Injury and Medical Countermeasure DevelopmentChanges in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometryDetermination of paclitaxel distribution in solid tumors by nano-particle assisted laser desorption ionization mass spectrometry imagingMALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarraysImaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in HypoxiaA method to prevent protein delocalization in imaging mass spectrometry of non-adherent tissues: application to small vertebrate lens imaging.Localized in situ hydrogel-mediated protein digestion and extraction technique for on-tissue analysis.MALDI imaging mass spectrometry: statistical data analysis and current computational challenges3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors.Interrogating the relationship between rat in vivo tissue distribution and drug property data for >200 structurally unrelated molecules.Metabolite localization by atmospheric pressure high-resolution scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging in whole-body sections and individual organs of the rove beetle Paederus riparius.A Nanostructured Matrices Assessment to Study Drug Distribution in Solid Tumor Tissues by Mass Spectrometry Imaging.Laser ablation ICP-MS for quantitative biomedical applications.Mass spectrometry-based tissue imaging of small moleculesCyclotides associate with leaf vasculature and are the products of a novel precursor in petunia (Solanaceae)Mapping antiretroviral drugs in tissue by IR-MALDESI MSI coupled to the Q Exactive and comparison with LC-MS/MS SRM assay.A new combination MALDI matrix for small molecule analysis: application to imaging mass spectrometry for drugs and metabolites.MALDI imaging in human skin tissue sections: focus on various matrices and enzymes.Quantitative imaging of a therapeutic peptide in biological tissue sections by MALDI MS.Current frontiers in clinical research application of MALDI imaging mass spectrometry.Matrix assisted laser desorption ionization imaging mass spectrometry workflow for spatial profiling analysis of N-linked glycan expression in tissuesThe significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution.Matrix-assisted laser desorption/ionization mass spectrometry imaging of cardiolipins in rat organ sections.Alternative two-step matrix application method for imaging mass spectrometry to avoid tissue shrinkage and improve ionization efficiency.MALDI mass spectrometry imaging of 1-methyl-4-phenylpyridinium (MPP+) in mouse brain.MALDI imaging mass spectrometry profiling of proteins and lipids in clear cell renal cell carcinomaQuantification of small molecule drugs in biological tissue sections by imaging mass spectrometry using surrogate tissue-based calibration standardsAnalysis of trace fibers by IR-MALDESI imaging coupled with high resolving power MS.MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice.Spatially resolved quantification of gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI.Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration.Imaging MALDI MS of Dosed Brain Tissues Utilizing an Alternative Analyte Pre-extraction Approach.Assessing drug and metabolite detection in liver tissue by UV-MALDI and IR-MALDESI mass spectrometry imaging coupled to FT-ICR MS.High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling.Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling.Influence of C-Trap Ion Accumulation Time on the Detectability of Analytes in IR-MALDESI MSI.
P2860
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P2860
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@ast
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@en
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@nl
type
label
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@ast
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@en
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@nl
prefLabel
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@ast
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@en
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@nl
P2093
P356
P1433
P1476
MALDI imaging mass spectrometry: bridging biology and chemistry in drug development.
@en
P2093
David Wagner
M Reid Groseclose
Stephen Castellino
P304
P356
10.4155/BIO.11.232
P577
2011-11-01T00:00:00Z