Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
about
Novel therapeutic strategies for multiple myelomaRenal Toxicities of Novel Agents Used for Treatment of Multiple Myeloma.Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell linesSmall molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myelomaCytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.UCHL1 is a biomarker of aggressive multiple myeloma required for disease progressionAmblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell.SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism.MUC1-C drives MYC in multiple myelomaEndoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy.The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma.Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition.Progress and Paradigms in Multiple Myeloma.MUC1-C is a target in lenalidomide resistant multiple myeloma.Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines.PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise.Modeling Multiple Myeloma-Bone Marrow interactions and response to drugs in a 3D surrogate microenvironment.Crosstalk between Apoptosis and Autophagy is Regulated by the Arginylated BiP/Beclin-1/p62 Complex.Network-Based Analysis of Bortezomib Pharmacodynamic Heterogeneity in Multiple Myeloma Cells.
P2860
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P2860
Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@ast
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@en
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@nl
type
label
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@ast
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@en
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@nl
prefLabel
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@ast
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@en
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@nl
P2093
P2860
P1433
P1476
Selective and potent Akt inhib ...... uced by proteasome inhibition.
@en
P2093
Atsushi Iwama
Diana Cirstea
Francesca Cottini
Gullu Gorgun
Hiroto Ohguchi
Jana Jakubikova
Jiro Minami
Naoya Mimura
Rikio Suzuki
P2860
P304
P356
10.1158/0008-5472.CAN-13-3652
P407
P577
2014-06-16T00:00:00Z