Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae
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Metabolic Flexibility and Dysfunction in Cardiovascular CellsKnockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cellsExploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.Coronary Artery Disease-Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes.Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismAlteration of lysosome fusion and low-grade inflammation mediated by super-low-dose endotoxin.Autophagy: an emerging therapeutic target in vascular diseasesDihydroaustrasulfone Alcohol (WA-25) Impedes Macrophage Foam Cell Formation by Regulating the Transforming Growth Factor-β1 Pathway.Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?Macrophage Phenotype and Function in Different Stages of Atherosclerosis.Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice.Clofazimine Biocrystal Accumulation in Macrophages Upregulates Interleukin 1 Receptor Antagonist Production To Induce a Systemic Anti-Inflammatory StateChronic Iron Overload Results in Impaired Bacterial Killing of THP-1 Derived Macrophage through the Inhibition of Lysosomal AcidificationInclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosisDegradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis.Hypericin-mediated sonodynamic therapy induces autophagy and decreases lipids in THP-1 macrophage by promoting ROS-dependent nuclear translocation of TFEB.Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity.Non-traditional cytokines: How catecholamines and adipokines influence macrophages in immunity, metabolism and the central nervous system.Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment.Cysteine proteases in atherosclerosis.Foam cell formation by particulate matter (PM) exposure: a review.microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis.Transcription factor EB: from master coordinator of lysosomal pathways to candidate therapeutic target in degenerative storage diseases.Lipids, lysosomes, and autophagy.Target acquired: Selective autophagy in cardiometabolic disease.Coronary Atherosclerotic Vulnerable Plaque: Current PerspectivesRole of NLRP3 Inflammasomes in Atherosclerosis.Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells.Inhibition of mTOR reduces lipotoxic cell death in primary macrophages through an autophagy-independent mechanismModeling of autophagy-related gene expression dynamics during long term fasting in European eel (Anguilla anguilla).The crystal-induced activation of NLRP3 inflammasomes in atherosclerosis.The physiological determinants of drug-induced lysosomal stress resistance.Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation.CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report.Cytosolic lipolysis and lipophagy: two sides of the same coin.Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device.Cholesterol efflux in the transplant patient.Gypenoside XVII Enhances Lysosome Biogenesis and Autophagy Flux and Accelerates Autophagic Clearance of Amyloid-β through TFEB Activation.Classical and alternative roles for autophagy in lipid metabolism.
P2860
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P2860
Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Induction of lysosomal biogene ...... nction and downstream sequelae
@ast
Induction of lysosomal biogene ...... nction and downstream sequelae
@en
Induction of lysosomal biogene ...... nction and downstream sequelae
@nl
type
label
Induction of lysosomal biogene ...... nction and downstream sequelae
@ast
Induction of lysosomal biogene ...... nction and downstream sequelae
@en
Induction of lysosomal biogene ...... nction and downstream sequelae
@nl
prefLabel
Induction of lysosomal biogene ...... nction and downstream sequelae
@ast
Induction of lysosomal biogene ...... nction and downstream sequelae
@en
Induction of lysosomal biogene ...... nction and downstream sequelae
@nl
P2093
P2860
P50
P1476
Induction of lysosomal biogene ...... nction and downstream sequelae
@en
P2093
Abhinav Diwan
Ismail Sergin
Jaleisa Turner
Roy Emanuel
Somashubhra Bhattacharya
P2860
P304
P356
10.1161/ATVBAHA.114.303342
P407
P577
2014-07-24T00:00:00Z