Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease - Wikidata - wikimedia - TriplyDB

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

http://www.wikidata.org/entity/Q34077884

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The role of RecQ helicases in non-homologous end-joining Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis Systematic analysis of fly models with multiple drivers reveals different effects of ataxin-1 and huntingtin in neuron subtype-specific expression Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes.Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans.Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease.Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease.Oxidative DNA damage in neurons: implication of ku in neuronal homeostasis and survival.Lithium chloride alleviates neurodegeneration partly by inhibiting activity of GSK3β in a SCA3 Drosophila model.

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P2860

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

http://www.wikidata.org/entity/Q34077884

description

2011 nî lūn-bûn

@nan

2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@ast

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@en

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@nl

type

label

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@ast

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@en

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@nl

prefLabel

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@ast

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@en

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@nl

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JOURNAL.PONE.0027408

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Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease

@en

P2093

Hitoshi Okazawa

http://www.w3.org/2001/XMLSchema#string

Kazuhiko Tagawa

http://www.w3.org/2001/XMLSchema#string

Masaki Sone

http://www.w3.org/2001/XMLSchema#string

Takeshi Iwatsubo

http://www.w3.org/2001/XMLSchema#string

Takuya Tamura

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P2860

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease.

PQBP-1/Npw38, a nuclear protein binding to the polyglutamine tract, interacts with U5-15kD/dim1p via the carboxyl-terminal domain

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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e27408

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scholarly article

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10.1371/JOURNAL.PONE.0027408

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11

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6

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2011-11-07T00:00:00Z

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51808647

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22096569

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Huntington disease

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3210167

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