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Ribosomal route to small-molecule diversity

Ribosomal route to small-molecule diversity

http://www.wikidata.org/entity/Q34080175

about

Biocatalysts and small molecule products from metagenomic studies Structure of PatF fromProchloron didemni Predominately Uncultured Microbes as Sources of Bioactive Agents Host control of symbiont natural product chemistry in cryptic populations of the tunicate Lissoclinum patella The secret to a successful relationship: lasting chemistry between ascidians and their symbiotic bacteria Aestuaramides, a natural library of cyanobactin cyclic peptides resulting from isoprene-derived Claisen rearrangements.Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants.Recent advances in natural product discovery.Structure and mechanism of lanthipeptide biosynthetic enzymes.Assessing the combinatorial potential of the RiPP cyanobactin tru pathway Recognition sequences and substrate evolution in cyanobactin biosynthesis Facile Removal of Leader Peptides from Lanthipeptides by Incorporation of a Hydroxy Acid Combinatorial biosynthesis of RiPPs: docking with marine life.An engineered lantibiotic synthetase that does not require a leader peptide on its substrate.Nonribosomal Peptide Synthesis-Principles and Prospects.Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge.Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase.Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product.Metabolic model for diversity-generating biosynthesis New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis.Recombinant thiopeptides containing noncanonical amino acids.Insights into the mechanism of peptide cyclodehydrations achieved through the chemoenzymatic generation of amide derivatives.Engineering unnatural variants of plantazolicin through codon reprogramming.Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis.Synthetic biological approaches to natural product biosynthesis.Emerging trends in the discovery of natural product antibacterials.The origins of cyanobactin chemistry and biology.The structural biology of patellamide biosynthesis YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.Directing Biosynthesis: Practical Supply of Natural and Unnatural Cyanobactins.Modularity of RiPP Enzymes Enables Designed Synthesis of Decorated Peptides.Unique post-translational oxime formation in the biosynthesis of the azolemycin complex of novel ribosomal peptides from Streptomyces sp. FXJ1.264 In Vitro Biosynthesis and Substrate Tolerance of the Plantazolicin Family of Natural Products.Expanding the chemical diversity of lasso peptide MccJ25 with genetically encoded noncanonical amino acids.Cyanobacterial Sfp-type phosphopantetheinyl transferases functionalize carrier proteins of diverse biosynthetic pathways.Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo.Thiazoline peptides and a tris-phenethyl urea from Didemnum molle with anti-HIV activity.Bioinspired strategy for the ribosomal synthesis of thioether-bridged macrocyclic peptides in bacteria.

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P2860

Ribosomal route to small-molecule diversity

http://www.wikidata.org/entity/Q34080175

description

2011 nî lūn-bûn

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2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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type

label

Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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Ribosomal route to small-molecule diversity

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Journal of the American Chemical Society

P1476

Ribosomal route to small-molecule diversity

@en

P2093

Eric W Schmidt

http://www.w3.org/2001/XMLSchema#string

Ma Diarey B Tianero

http://www.w3.org/2001/XMLSchema#string

Mohamed S Donia

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Peter G Schultz

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Travis S Young

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P2860

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

Solution structure of the leader sequence of the patellamide precursor peptide, PatE1-34

Introducing lasso peptides as molecular scaffolds for drug design: engineering of an integrin antagonist

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

Variation in tropical reef symbiont metagenomes defined by secondary metabolism

Cloning and engineering of the cinnamycin biosynthetic gene cluster from Streptomyces cinnamoneus cinnamoneus DSM 40005

Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli.

Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle.

Production of lantipeptides in Escherichia coli.

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418-425

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scholarly article

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10.1021/JA208278K

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1

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134

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22107593

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3268757

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