A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1. - Wikidata - wikimedia - TriplyDB

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

http://www.wikidata.org/entity/Q34084039

about

Pathogen recognition and activation of the innate immune response in zebrafish Revisiting Crohn's disease as a primary immunodeficiency of macrophages The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease Regulation of IL-10 and IL-12 production and function in macrophages and dendritic cells Role of Nucleotide-binding and Oligomerization Domain 2 Protein (NOD2) in the Development of Atherosclerosis Inflammatory bowel disease NOD2-mediated suppression of CD55 on neutrophils enhances C5a generation during polymicrobial sepsis.Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance.Variation in NOD2 augments Th2- and Th17 responses to myelin basic protein in multiple sclerosis Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production.Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells.Crohn's disease: NOD2, autophagy and ER stress converge.Large-vessel granulomatous vasculitis in Crohn's disease: a clinical pathology conference held by the division of rheumatology at hospital for special surgery A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology.Nod2: a key regulator linking microbiota to intestinal mucosal immunity.Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis.Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins NOD1 and NOD2: signaling, host defense, and inflammatory disease.Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice.Relationship between gut microbiota and development of T cell associated disease.Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.The gut microbiota and inflammatory bowel disease.Endogenous interleukin-10 constrains Th17 cells in patients with inflammatory bowel disease.Interactions of the innate and adaptive arms of the immune system in the pathogenesis of spondyloarthritis Immunopathogenesis of IBD: current state of the art.Autophagy, microbial sensing, endoplasmic reticulum stress, and epithelial function in inflammatory bowel disease Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa.Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.Small molecule tyrosine kinase inhibitors for the treatment of intestinal inflammation HnRNP A1 is Involved in Deep Vein Thrombosis Patients with Behçet's Disease Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis.L1 penalized continuation ratio models for ordinal response prediction using high-dimensional datasets A novel approach to detect cumulative genetic effects and genetic interactions in Crohn's disease.NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease.Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.Morbus Crohn--a disease of failing macroautophagy in the immune system?

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P2860

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

http://www.wikidata.org/entity/Q34084039

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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A Crohn's disease-associated N ...... ar ribonucleoprotein hnRNP-A1.

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A Crohn's disease-associated N ...... ar ribonucleoprotein hnRNP-A1.

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A Crohn's disease-associated N ...... ar ribonucleoprotein hnRNP-A1.

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A Crohn's disease-associated N ...... ar ribonucleoprotein hnRNP-A1.

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P2093

Eiichiro Noguchi

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Mihai G Netea

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Xiaojing Ma

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Xiaoyan Kang

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Yoichiro Homma

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P2860

Inflammatory Bowel Disease

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice

The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways

Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-gamma-primed IL-12 production by IFN regulatory factor 1

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471-479

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10.1038/NI.1722

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5

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10

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24260983

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19349988

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Crohn's disease

ribonucleoprotein

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2928218

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