A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
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Augmenting the Efficacy of Immunotoxins and Other Targeted Protein Toxins by Endosomal Escape EnhancersObstructing toxin pathways by targeted pore blockageGRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.Coupling immunomagnetic separation on magnetic beads with matrix-assisted laser desorption ionization-time of flight mass spectrometry for detection of staphylococcal enterotoxin BEssential lysine residues within transmembrane helix 1 of diphtheria toxin facilitate COPI binding and catalytic domain entrySL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemia.Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen.Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process.From structure to solutions: the role of basic research in developing anthrax countermeasures: Microbiology Graduate Program Seminar: Anthrax toxin.Trojan horse or proton force: finding the right partner(s) for toxin translocation.COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.Clostridial toxins.Exploring the role of host cell chaperones/PPIases during cellular up-take of bacterial ADP-ribosylating toxins as basis for novel pharmacological strategies to protect mammalian cells against these virulence factors.Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells.Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.Increased RNAi is related to intracellular release of siRNA via a covalently attached signal peptide.Pet, a non-AB toxin, is transported and translocated into epithelial cells by a retrograde trafficking pathway.Defensive strategies of Bacillus anthracis that promote a fatal disease.Topography of the hydrophilic helices of membrane-inserted diphtheria toxin T domain: TH1-TH3 as a hydrophilic tetherThe membrane topography of the diphtheria toxin T domain linked to the a chain reveals a transient transmembrane hairpin and potential translocation mechanisms.
P2860
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P2860
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A conserved motif in transmemb ...... omain delivery to the cytosol.
@ast
A conserved motif in transmemb ...... omain delivery to the cytosol.
@en
A conserved motif in transmemb ...... omain delivery to the cytosol.
@nl
type
label
A conserved motif in transmemb ...... omain delivery to the cytosol.
@ast
A conserved motif in transmemb ...... omain delivery to the cytosol.
@en
A conserved motif in transmemb ...... omain delivery to the cytosol.
@nl
prefLabel
A conserved motif in transmemb ...... omain delivery to the cytosol.
@ast
A conserved motif in transmemb ...... omain delivery to the cytosol.
@en
A conserved motif in transmemb ...... omain delivery to the cytosol.
@nl
P2093
P2860
P356
P1476
A conserved motif in transmemb ...... omain delivery to the cytosol.
@en
P2093
Carolina Trujillo
Johanna vanderSpek
John R Murphy
Robert Harrison
Ryan Ratts
P2860
P304
15635-15640
P356
10.1073/PNAS.0504937102
P407
P577
2005-10-17T00:00:00Z