Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression.
about
Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cellsRegulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotypeNotch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinasesNotch Signaling in Neuroendocrine TumorsTargeting the Notch signaling pathway in cancer therapeuticsFrom fly wings to targeted cancer therapies: a centennial for notch signalingIntravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cellsCharacterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cellsNotch signalling pathway as an oncogenic factor involved in cancer developmentImatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanomaNotch inhibitors as a new tool in the war on cancer: a pathway to watch.Inferring data-specific micro-RNA function through the joint ranking of micro-RNA and pathways from matched micro-RNA and gene expression data.Notch1 activation is a poor prognostic factor in patients with gastric cancer.Oncogenic BRAFV600E induces expression of neuronal differentiation marker MAP2 in melanoma cells by promoter demethylation and down-regulation of transcription repressor HES1.Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biologyIdentification of E-selectin as a novel target for the regulation of postnatal neovascularization: implications for diabetic wound healing.Myricetin induces apoptosis and enhances chemosensitivity in ovarian cancer cells.FBXW7 mutations in melanoma and a new therapeutic paradigmInhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1.Notch inhibitors for cancer treatment.A Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth.The role of microRNAs and long non-coding RNAs in the pathology, diagnosis, and management of melanomaA ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.The different role of Notch1 and Notch2 in astrocytic gliomasTargeting Nodal in malignant melanoma cells.Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth.The roles of Notch3 on the cell proliferation and apoptosis induced by CHIR99021 in NSCLC cell lines: a functional link between Wnt and Notch signaling pathwaysVimentin and Notch as biomarkers for breast cancer progressionMRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma.Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice.UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest-Like Cells via Suppression of Notch.Epigenetic reprogramming of melanoma cells by vitamin C treatmentNotch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion.Single nucleotide polymorphism microarray analysis in cortisol-secreting adrenocortical adenomas identifies new candidate genes and pathways.Extrafollicular dermal melanocyte stem cells and melanomaDirecting and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating.Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma.Notch1 Autoactivation via Transcriptional Regulation of Furin, Which Sustains Notch1 Signaling by Processing Notch1-Activating Proteases ADAM10 and Membrane Type 1 Matrix MetalloproteinaseA distinct gene expression signature characterizes human neuroblastoma cancer stem cells.
P2860
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P2860
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Activation of Notch1 signaling ...... primary melanoma progression.
@ast
Activation of Notch1 signaling ...... primary melanoma progression.
@en
Activation of Notch1 signaling ...... primary melanoma progression.
@nl
type
label
Activation of Notch1 signaling ...... primary melanoma progression.
@ast
Activation of Notch1 signaling ...... primary melanoma progression.
@en
Activation of Notch1 signaling ...... primary melanoma progression.
@nl
prefLabel
Activation of Notch1 signaling ...... primary melanoma progression.
@ast
Activation of Notch1 signaling ...... primary melanoma progression.
@en
Activation of Notch1 signaling ...... primary melanoma progression.
@nl
P2093
P2860
P356
P1476
Activation of Notch1 signaling ...... primary melanoma progression.
@en
P2093
Akinobu Soma
Anthony J Capobianco
Chelsea C Pinnix
Eric J Brown
Imre Veres
Istvan Juhasz
Klara Balint
Zhao-Jun Liu
P2860
P304
P356
10.1172/JCI25001
P407
P577
2005-10-20T00:00:00Z