Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway. - Wikidata - wikimedia - TriplyDB

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

http://www.wikidata.org/entity/Q34085728

about

Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscle Diacylglycerol Kinases in T Cell Tolerance and Effector Function Metformin as a new anti-cancer drug in adrenocortical carcinoma Cell autonomous lipin 1 function is essential for development and maintenance of white and brown adipose tissue Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.Phosphatidic acid enhances mTOR signaling and resistance exercise induced hypertrophy.NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells.REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling.Mechanical stimulation induces mTOR signaling via an ERK-independent mechanism: implications for a direct activation of mTOR by phosphatidic acid.Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation Relative Expression Levels Rather Than Specific Activity Plays the Major Role in Determining In Vivo AKT Isoform Substrate Specificity.A dual role for diacylglycerol kinase generated phosphatidic acid in autoantibody-induced neutrophil exocytosis.Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine.Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes.Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men The effects of phosphatidic acid supplementation on strength, body composition, muscular endurance, power, agility, and vertical jump in resistance trained men.Regulation of Lipid Signaling by Diacylglycerol Kinases during T Cell Development and Function Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes.Sustained PKCβII activity confers oncogenic properties in a phospholipase D- and mTOR-dependent manner.A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis.Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling.Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle Signal transduction in inherited metabolic disorders: a model for a possible pathogenetic mechanism.Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1.The mechanistic and ergogenic effects of phosphatidic acid in skeletal muscle."Nutraceuticals" in relation to human skeletal muscle and exercise.Phosphatidic acid: biosynthesis, pharmacokinetics, mechanisms of action and effect on strength and body composition in resistance-trained individuals.Modulation of oxidative stress and tau phosphorylation by the mTOR activator phosphatidic acid in SH-SY5Y cells.Effects of oral phosphatidic acid feeding with or without whey protein on muscle protein synthesis and anabolic signaling in rodent skeletal muscle.Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.Targeted therapy in sarcomas: mammalian target of rapamycin inhibitors from bench to bedside.Phospholipase D inhibitors reduce human prostate cancer cell proliferation and colony formation.Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.Markers and Biomarkers of Endothelium: When Something Is Rotten in the State.The Mitotic and Metabolic Effects of Phosphatidic Acid in the Primary Muscle Cells of Turbot (Scophthalmus maximus).

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Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

http://www.wikidata.org/entity/Q34085728

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@ast

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@en

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@nl

type

label

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@ast

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@en

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@nl

prefLabel

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@ast

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@en

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

@nl

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AJPCELL.00039.2010

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American Journal of Physiology - Cell Physiology

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Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.

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P2093

Jeremiah N Winter

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Leonard S Jefferson

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Scot R Kimball

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Todd E Fox

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P2860

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Regulation of mTOR and cell growth in response to energy stress by REDD1.

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR

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