Implications of epidermal growth factor (EGF) induced egf receptor aggregation
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Computational modeling reveals molecular details of epidermal growth factor bindingStructural Basis for Negative Cooperativity in Growth Factor Binding to an EGF ReceptorMembrane interaction of bound ligands contributes to the negative binding cooperativity of the EGF receptorSingle-molecule analysis of epidermal growth factor binding on the surface of living cells.Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cellsSingle-molecule analysis of epidermal growth factor signaling that leads to ultrasensitive calcium responseThe logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput dataMechanisms of activation of receptor tyrosine kinases: monomers or dimers.Kinetic analysis of high affinity forms of interleukin (IL)-13 receptors: suppression of IL-13 binding by IL-2 receptor gamma chain.Use of mechanistic models to integrate and analyze multiple proteomic datasetsHeterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system.Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activationAmphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.Ligand affinity and kinase activity are independent of bacterial chemotaxis receptor concentration: insight into signaling mechanisms.Exploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach.Negative co-operativity in the EGF receptor.Ligand-induced ErbB receptor dimerization.Interaction of antibodies with ErbB receptor extracellular regions.The EGFR family: not so prototypical receptor tyrosine kinases.Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors.Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The "Rotation Model".Heterogeneities in EGF receptor density at the cell surface can lead to concave up scatchard plot of EGF binding.Dimerization-based control of cooperativityElementary steps in T cell receptor triggering.Thermodynamic mixing of molecular states of the epidermal growth factor receptor modulates macroscopic ligand binding affinity.
P2860
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P2860
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@ast
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@en
Implications of epidermal growth factor
@nl
type
label
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@ast
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@en
Implications of epidermal growth factor
@nl
prefLabel
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@ast
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@en
Implications of epidermal growth factor
@nl
P2093
P2860
P1433
P1476
Implications of epidermal growth factor (EGF) induced egf receptor aggregation
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(92)81572-2
P407
P577
1992-07-01T00:00:00Z