Spinal 5-HT7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-Desmethyltramadol, via activation of descending serotonergic pathways.
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Tramadol Extended-Release for the Management of Pain due to OsteoarthritisRole of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.Role of the 5-HT7 receptor in the central nervous system: from current status to future perspectives.5-HT7 receptors are involved in neurogenic dural vasodilatation in an experimental model of migraine.Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of ratsTramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic MechanismsAnalgesic Efficacy of Firocoxib, a Selective Inhibitor of Cyclooxygenase 2, in a Mouse Model of Incisional Pain.Inhibition of bladder overactivity by a combination of tibial neuromodulation and tramadol treatment in cats.Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitroAntinociceptive effects of vitexin in a mouse model of postoperative painRole of spinal neurotransmitter receptors in itch: new insights into therapies and drug development.Extended-release formulations of tramadol in the treatment of chronic pain.The mu-opioid receptor agonist/noradrenaline reuptake inhibition (MOR-NRI) concept in analgesia: the case of tapentadol.Efficacy of various analgesics on shoulder function and rotator cuff tendon-to-bone healing in a rat (Rattus norvegicus) model.Opioid adjuvant strategy: improving opioid effectiveness.Analgesic effects of tramadol, tramadol-gabapentin, and buprenorphine in an incisional model of pain in rats (Rattus norvegicus).Assessment of 5-HT(7) Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versus Wild-Type Mice.PharmGKB summary: tramadol pathway.Discovery and development of tramadol for the treatment of pain.The antinociceptive effect of intrathecal tramadol in rats: the role of alpha 2-adrenoceptors in the spinal cord.5-HT7 Receptors Are Not Involved in Neuropeptide Release in Primary Cultured Rat Trigeminal Ganglion Neurons.Depressing interleukin-1β contributed to the synergistic effects of tramadol and minocycline on spinal nerve ligation-induced neuropathic pain.
P2860
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P2860
Spinal 5-HT7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-Desmethyltramadol, via activation of descending serotonergic pathways.
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2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
@ast
Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
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P2093
P1433
P1476
Spinal 5-HT7 receptors play an ...... cending serotonergic pathways.
@en
P2093
Ahmet Dogrul
Ali Sizlan
Altan Sahin
Ercan Kurt
Melik Seyrek
Omer Yanarates
Orhan Kozak
Ozgür Akgül
Ulku Aypar
Vedat Yildirim
P304
P356
10.1097/ALN.0B013E3181CD7920
P407
P577
2010-03-01T00:00:00Z