Structure and dynamics of a processive Brownian motor: the translating ribosome
about
Structural insights into ribosome translocationTorque, chemistry and efficiency in molecular motors: a study of the rotary-chemical coupling in F1-ATPaseInitiation of mRNA translation in bacteria: structural and dynamic aspectsBeyond DNA origami: the unfolding prospects of nucleic acid nanotechnologyRedundancy of the genetic code enables translational pausingConformational dynamics in phosphoglycerate kinase, an open and shut case?smFRET studies of the 'encounter' complexes and subsequent intermediate states that regulate the selectivity of ligand bindingFrameshifting dynamicsMolecular dynamics of EF-G during translocationMechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureusAllosteric control of the ribosome by small-molecule antibiotics.Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosomeStructural characterization of mRNA-tRNA translocation intermediatesStructure of the ribosome with elongation factor G trapped in the pretranslocation stateThe ribosome as a molecular machine: the mechanism of tRNA-mRNA movement in translocationMajor centers of motion in the large ribosomal RNAsOrigin and evolution of the ribosomeLikelihood-based classification of cryo-EM images using FREALIGNBiased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.Trajectories of the ribosome as a Brownian nanomachine.Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM.The impact of recent improvements in cryo-electron microscopy technology on the understanding of bacterial ribosome assembly.Hierarchy of RNA functional dynamics.A microfluidic approach for investigating the temperature dependence of biomolecular activity with single-molecule resolution.Codon-by-codon modulation of translational speed and accuracy via mRNA folding.The ribosome uses cooperative conformational changes to maximize and regulate the efficiency of translation.The Ribosome Comes AliveAntibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation.Codon-dependent tRNA fluctuations monitored with fluorescence polarization.Mechanisms of cellular proteostasis: insights from single-molecule approachesStructural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryogenic electron microscopy.Movement of elongation factor G between compact and extended conformations.Biological mechanisms, one molecule at a timeValidation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coliTransfer RNA-mediated regulation of ribosome dynamics during protein synthesis.The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesisAllosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesisElectrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase.Functional complexity and regulation through RNA dynamicsQuantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome.
P2860
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P2860
Structure and dynamics of a processive Brownian motor: the translating ribosome
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structure and dynamics of a processive Brownian motor: the translating ribosome
@ast
Structure and dynamics of a processive Brownian motor: the translating ribosome
@en
Structure and dynamics of a processive Brownian motor: the translating ribosome
@nl
type
label
Structure and dynamics of a processive Brownian motor: the translating ribosome
@ast
Structure and dynamics of a processive Brownian motor: the translating ribosome
@en
Structure and dynamics of a processive Brownian motor: the translating ribosome
@nl
prefLabel
Structure and dynamics of a processive Brownian motor: the translating ribosome
@ast
Structure and dynamics of a processive Brownian motor: the translating ribosome
@en
Structure and dynamics of a processive Brownian motor: the translating ribosome
@nl
P2860
P1476
Structure and dynamics of a processive Brownian motor: the translating ribosome
@en
P2093
Ruben L Gonzalez
P2860
P304
P356
10.1146/ANNUREV-BIOCHEM-060408-173330
P577
2010-01-01T00:00:00Z