Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors.
about
Structure-analysis of the HIV-1 integrase Y143C/R raltegravir resistance mutation in association with the secondary mutation T97AResistance mutations outside the integrase coding region have an effect on human immunodeficiency virus replicative fitness but do not affect its susceptibility to integrase strand transfer inhibitorsHIV-1 integrase resistance among antiretroviral treatment naive and experienced patients from Northwestern Poland.Analysis of low-frequency mutations associated with drug resistance to raltegravir before antiretroviral treatment.Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapyComparison of illumina and 454 deep sequencing in participants failing raltegravir-based antiretroviral therapy.Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient.G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to raltegravir whereas Y143C does not.Study of genotypic and phenotypic HIV-1 dynamics of integrase mutations during raltegravir treatment: a refined analysis by ultra-deep 454 pyrosequencing.Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome.Clinical implications of HIV-1 minority variantsImpact of primary elvitegravir resistance-associated mutations in HIV-1 integrase on drug susceptibility and viral replication fitnessRole of raltegravir in HIV-1 management.Longitudinal analysis of integrase N155H variants in heavily treated patients failing raltegravir-based regimens.Successful Prevention of Transmission of Integrase Resistance in the Swiss HIV Cohort Study.The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness.Prevalence of primary resistance mutations to integrase inhibitors in treatment-naïve and -experienced patients infected with B and non-B HIV-1 variants.Genotypic and Phylogenetic Insights on Prevention of the Spread of HIV-1 and Drug Resistance in "Real-World" Settings.
P2860
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P2860
Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Secondary integrase resistance ...... ility to integrase inhibitors.
@ast
Secondary integrase resistance ...... ility to integrase inhibitors.
@en
Secondary integrase resistance ...... ility to integrase inhibitors.
@nl
type
label
Secondary integrase resistance ...... ility to integrase inhibitors.
@ast
Secondary integrase resistance ...... ility to integrase inhibitors.
@en
Secondary integrase resistance ...... ility to integrase inhibitors.
@nl
prefLabel
Secondary integrase resistance ...... ility to integrase inhibitors.
@ast
Secondary integrase resistance ...... ility to integrase inhibitors.
@en
Secondary integrase resistance ...... ility to integrase inhibitors.
@nl
P2093
P2860
P50
P356
P1476
Secondary integrase resistance ...... bility to integrase inhibitors
@en
P2093
Daniele Armenia
Evelien Rondelez
Fernanda Scopelliti
Francesca Ceccherini-Silberstein
Guido Palamara
Kurt Van Baelen
Liesbeth Van Wesenbeeck
Lieven J Stuyver
Maria Trignetti
P2860
P304
P356
10.1128/AAC.01720-09
P407
P577
2010-05-17T00:00:00Z