Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
about
The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinaseActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesDysregulation of X-linked gene expression in Klinefelter's syndrome and association with verbal cognitionTargeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like CellsInhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retinaWee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumptionERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsLocalization and dynamics of Cdc2-cyclin B during meiotic reinitiation in starfish oocytesPI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.Entry into mitosis: a solution to the decades-long enigma of MPFGuanine nucleotides in the meiotic maturation of starfish oocytes: regulation of the actin cytoskeleton and of Ca(2+) signaling.Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor modelsThe Polo-like kinase Plx1 interacts with and inhibits Myt1 after fertilization of Xenopus eggs.Akt phosphorylation at Ser473 predicts benefit of paclitaxel chemotherapy in node-positive breast cancer.Regulation of intracellular pH by p90Rsk-dependent activation of an Na(+)/H(+) exchanger in starfish oocytes.Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A.Mos is not required for the initiation of meiotic maturation in Xenopus oocytes.Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.Akt: a double-edged sword in cell proliferation and genome stability.Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways.Multisite phosphorylation of nuclear interaction partner of ALK (NIPA) at G2/M involves cyclin B1/Cdk1.MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells.Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation.Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma.Calcium at fertilization and in early developmentMicroRNA-126 is down-regulated in human esophageal squamous cell carcinoma and inhibits the proliferation and migration in EC109 cell via PI3K/AKT signaling pathway.Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis.Involvement of polo-like kinase 1 (Plk1) in mitotic arrest by inhibition of mitogen-activated protein kinase-extracellular signal-regulated kinase-ribosomal S6 kinase 1 (MEK-ERK-RSK1) cascadeDistinct regulators for Plk1 activation in starfish meiotic and early embryonic cycles.Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exitAn IGF1/insulin receptor substrate-1 pathway stimulates a mitotic kinase (cdk1) in the uterine epithelium during the proliferative response to estradiol.Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor.Drosophila myt1 is the major cdk1 inhibitory kinase for wing imaginal disc development.Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signalingProapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer.Cyclin aggregation and robustness of bio-switching.
P2860
Q24553550-D872F518-2BBE-4733-808D-65DFDA7C429EQ24632768-24A925E2-CCE1-4F7E-9398-D7D73B678A51Q24671639-77899F49-5926-4340-8426-60C062E9E65BQ26775940-353CA0C2-E7FF-43BD-8360-7ADE39A606DBQ27320024-29B92ABF-69DE-4DFF-93E4-DADE95B3E43BQ28484771-D2ADAF61-A304-4DF5-BF5D-AE9584B22141Q28505554-87373D0D-6F9A-4F27-A3A5-41C83E869CC8Q29615216-4CE98587-14AC-4FCE-B2D1-1466E2BE5A62Q30486993-545D4509-D958-4B31-B2C2-724FC9701207Q30540402-BF4FC2BD-7429-4546-B759-E0C05AAEABF4Q30781595-A72891BE-AFE5-4622-93DF-5D74A20EF4E9Q33360123-B6C601BA-208B-4F42-ADDD-3E5D80083389Q33484168-97FB1D31-E712-4F59-9A51-F3D738D771CDQ33578960-5117FB03-1ABA-4555-B5F8-684E5CDDB073Q33930739-6AD2ECBD-F256-4DF0-BE37-5CEB73679FF9Q33990934-1092E1E5-14E2-40FE-81FB-15AC76A54CA5Q34025231-0B31F4BB-079D-4C27-BBB0-C9BCEE3E10FAQ34047958-4E171EEA-1E8A-4468-8571-03EED1B0C7B8Q34090208-3FEE6F44-D024-4D5E-9C9E-FA7105822CDAQ34195806-2892C19D-E001-47FD-B509-FA4EFE5DA2FAQ34223641-0C7C9E05-3CC7-4051-9A9B-057333BA3486Q34280493-127492FB-A8D6-4016-81E1-475E9C418B9DQ34587399-C9966175-5175-4471-BA6C-EB333DABB7F4Q34612798-30AFA23C-A89F-4A7E-8F4D-275AA3C896F9Q35131665-2E26C3D0-0535-45F6-A3E4-92866DFD829FQ35222208-1C66ACE5-9F33-4174-8720-746FF0E73C9DQ35673519-1E10C5AB-C330-4D47-B06C-861CADF9DBD3Q35822230-FC5035CA-DC1B-4B9C-AD74-133868D9E75CQ35853951-6DC81CA0-CB62-4000-87BD-34C75F5F56B1Q35923996-77C1D87F-70E7-4A02-9539-B5B0DAD26D37Q35939835-E03D3AE3-749C-4F0F-9FE5-8BB0051834A3Q36267120-28F2AE7E-9140-4706-AF37-A0638C12FC9CQ36527208-4FF582BC-1805-4E8F-8D42-2A403E8D48C6Q36617409-97056A18-E9BB-46B5-8FE1-4F4AC4137590Q36856024-74679592-2A8A-470A-8A5C-69C29A93C93BQ37011398-35330922-50DD-4F6C-8EFA-7E42915E3FA2Q37106139-2CA6D388-E714-4172-B07D-C51FF21B493CQ37138122-FFD3996C-DFBC-4824-81F2-053167DB7615Q37145354-668BB1CD-7CFD-447B-9F9C-7509F9E4B332Q37155673-45FFD243-94E1-4770-BC74-88C822F5DB20
P2860
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@ast
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@en
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@nl
type
label
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@ast
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@en
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@nl
prefLabel
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@ast
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@en
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.
@nl
P2093
P2860
P356
P1433
P1476
Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition
@en
P2093
Eiichi Okumura
Hitoshi Yoshida
Kazunori Tachibana
Rie Kozutsumi
Shin-ichiro Hanada Si
Takeo Kishimoto
Takeshi Fukuhara
P2860
P2888
P304
P356
10.1038/NCB741
P50
P577
2002-02-01T00:00:00Z
P5875
P6179
1047889323