Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors.
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Identification of the binding sites of the SR49059 nonpeptide antagonist into the V1a vasopressin receptor using sulfydryl-reactive ligands and cysteine mutants as chemical sensorsCharacterization of a novel nonpeptide vasopressin V(2)-agonist, OPC-51803, in cells transfected human vasopressin receptor subtypesIdentification of the glycosylation sites utilized on the V1a vasopressin receptor and assessment of their role in receptor signalling and expressionEffects of YM471, a nonpeptide AVP V(1A) and V(2) receptor antagonist, on human AVP receptor subtypes expressed in CHO cells and oxytocin receptors in human uterine smooth muscle cellsCharacterization of SR 121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonistSodium excretion in response to vasopressin and selective vasopressin receptor antagonistsOxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptorsOxytocin and vasopressin enhance responsiveness to infant stimuli in adult marmosets.Conserved aromatic residues in the transmembrane region VI of the V1a vasopressin receptor differentiate agonist vs. antagonist ligand binding.The neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta)Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neuronsNeuroanatomical distribution of oxytocin and vasopressin 1a receptors in the socially monogamous coppery titi monkey (Callicebus cupreus).Real-time monitoring of changes in brain extracellular sodium and potassium concentrations and intracranial pressure after selective vasopressin-1a receptor inhibition following focal traumatic brain injury in rats.Development and therapeutic indications of orally-active non-peptide vasopressin receptor antagonists.Oxytocin and vasopressin agonists and antagonists as research tools and potential therapeutics.Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non-peptide oxytocin receptor agonist WAY 267,464: a biotelemetry study in rats.Selective vasopressin-1a receptor antagonist prevents brain edema, reduces astrocytic cell swelling and GFAP, V1aR and AQP4 expression after focal traumatic brain injury.Pharmacological profiling of neuropeptides on rabbit vaginal wall and vaginal artery smooth muscle in vitroV1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.Targeted over-expression of endothelin-1 in astrocytes leads to more severe brain damage and vasospasm after subarachnoid hemorrhage.Vasotocin and vasopressin stimulation of the chloride secretion in the human bronchial epithelial cell line, 16HBE14o-.Pharmacologic characterization of the oxytocin receptor in human uterine smooth muscle cells.Selectivity of d[Cha4]AVP and SSR149415 at human vasopressin and oxytocin receptors: evidence that SSR149415 is a mixed vasopressin V1b/oxytocin receptor antagonistOxytocin stimulates migration and invasion in human endothelial cells.Nephrogenic diabetes insipidus: essential insights into the molecular background and potential therapies for treatment.Vasopressin antagonists in the management of heart failure.Comparative Perspectives on Oxytocin and Vasopressin Receptor Research in Rodents and Primates: Translational Implications.Targeting platelets for prevention and treatment of cardiovascular disease.Fluorescent agonists and antagonists for vasopressin/oxytocin G protein-coupled receptors: usefulness in ligand screening assays and receptor studies.Pharmacological characterization of FE 201874, the first selective high affinity rat V1A vasopressin receptor agonist.Arginine Vasopressin Alters Both Spontaneous and Phase-Locked Synaptic Inputs to Airway Vagal Preganglionic Neuron via Activation of V1a Receptor: Insights into Stress-Related Airway Vagal Excitation.Identification of residues responsible for the selective binding of peptide antagonists and agonists in the V2 vasopressin receptor.Selective localization of oxytocin receptors and vasopressin 1a receptors in the human brainstem.Aquaporins in Brain Edema and Neuropathological Conditions.Effect of SR 49059, a V1a vasopressin receptor antagonist, in Raynaud's phenomenon.Biological characterization of rodent and human vasopressin V1b receptors using SSR-149415, a nonpeptide V1b receptor ligand.Systematic analysis of the entire second extracellular loop of the V(1a) vasopressin receptor: key residues, conserved throughout a G-protein-coupled receptor family, identified.Functional rescue of vasopressin V2 receptor mutants in MDCK cells by pharmacochaperones: relevance to therapy of nephrogenic diabetes insipidus.Pancreatic vasopressin V1b receptors: characterization in In-R1-G9 cells and localization in human pancreas.Arginine vasopressin ameliorates spatial learning impairments in chronic cerebral hypoperfusion via V1a receptor and autophagy signaling partially.
P2860
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P2860
Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors.
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@ast
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@en
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@nl
type
label
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@ast
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@en
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@nl
prefLabel
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@ast
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@en
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@nl
P2093
P2860
P356
P1476
Biochemical and pharmacologica ...... man vasopressin V1a receptors.
@en
P2093
Christophe B
Guiraudou P
Maffrand JP
Serradeil-Le Gal C
Villanova G
P2860
P304
P356
10.1172/JCI116554
P407
P577
1993-07-01T00:00:00Z