Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells.
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Abnormal levels of Gadd45alpha in developing neocortex impair neurite outgrowthHistone acetyltransferase inhibitors block neuroblastoma cell growth in vivoPhase 1 study of oral abexinostat, a histone deacetylase inhibitor, in combination with doxorubicin in patients with metastatic sarcoma.Phase 1 study of the oral histone deacetylase inhibitor abexinostat in patients with Hodgkin lymphoma, non-Hodgkin lymphoma, or chronic lymphocytic leukaemia.Wnt inhibitory factor 1 (WIF1) methylation and its association with clinical prognosis in patients with chondrosarcoma.RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinum on gastric cancer.Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell linesPCI-24781 (abexinostat), a novel histone deacetylase inhibitor, induces reactive oxygen species-dependent apoptosis and is synergistic with bortezomib in neuroblastoma.Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells.Synergistic inhibition of hepatocellular carcinoma growth by cotargeting chromatin modifying enzymes and poly (ADP-ribose) polymerases.The histone deacetylase inhibitor PCI-24781 as a putative radiosensitizer in pediatric glioblastoma cell lines.Role of Hydroxamate-Based Histone Deacetylase Inhibitors (Hb-HDACIs) in the Treatment of Solid MalignanciesTargeted therapies for bone sarcomas.Epigenetic alterations in osteosarcoma: promising targets.A polysaccharide from Trametes robiniophila Murrill induces apoptosis through intrinsic mitochondrial pathway in human osteosarcoma (U-2 OS) cells.Depression of focal adhesion kinase induces apoptosis in rat osteosarcoma OSR-6 cells in a caspase-dependent pathway.Bufalin inhibited the growth of human osteosarcoma MG-63 cells via down-regulation of Bcl-2/Bax and triggering of the mitochondrial pathway.Inhibition of focal adhesion kinase induces apoptosis in human osteosarcoma SAOS-2 cells.Matrine inhibited the growth of rat osteosarcoma UMR-108 cells by inducing apoptosis in a mitochondrial-caspase-dependent pathway.Role of epigenetic modulation for the treatment of sarcoma.Therapeutic applications of histone deacetylase inhibitors in sarcoma.Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2.Bone sarcomas: from biology to targeted therapies.Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.
P2860
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P2860
Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@ast
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@en
type
label
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@ast
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@en
prefLabel
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@ast
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@en
P2093
P2860
P1476
Histone deacetylase inhibitor ...... rubicin in bone sarcoma cells.
@en
P2093
Edwin Choy
Francis J Hornicek
Henry Mankin
Joseph H Schwab
Kirkham B Wood
Xianzhe Liu
Zhenfeng Duan
P2860
P2888
P304
P356
10.1007/S00280-010-1344-7
P577
2010-05-12T00:00:00Z
P6179
1028293907