Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila.
about
Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5Versatile roles of k63-linked ubiquitin chains in trafficking.Ubiquitin on ras: warden or partner in crime?RabGEF1/Rabex-5 Regulates TrkA-Mediated Neurite Outgrowth and NMDA-Induced Signaling Activation in NGF-Differentiated PC12 Cells.RalA and RalB proteins are ubiquitinated GTPases, and ubiquitinated RalA increases lipid raft exposure at the plasma membrane.Rabex-5 protein regulates the endocytic trafficking pathway of ubiquitinated neural cell adhesion molecule L1p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability.Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains hematopoietic homeostasis.Spatiotemporal regulation of the ubiquitinated cargo-binding activity of Rabex-5 in the endocytic pathway.RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.RABEX-5 overexpression in gastric cancer is correlated with elevated MMP-9 level.Meet me in the cytoplasm: A role for p27(Kip1) in the control of H-Ras.Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster.Ubiquitination: Added complexity in Ras and Rho family GTPase function.Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.CRL Ubiquitin Ligases and DNA Damage Response.Ubiquitin-dependent sorting in endocytosis.Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.Escorting Ras.CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling.Signal transduction: RABGEF1 fingers RAS for ubiquitination.
P2860
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P2860
Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@ast
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@en
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@nl
type
label
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@ast
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@en
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@nl
prefLabel
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@ast
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@en
Rabex-5 ubiquitin ligase activ ...... way homeostasis in Drosophila.
@nl
P2093
P2860
P1433
P1476
Rabex-5 ubiquitin ligase activ ...... hway homeostasis in Drosophila
@en
P2093
Cathie M Pfleger
Elizabeth A Horvath
Hsiu-Yu Liu
P2860
P304
P356
10.1016/J.CUB.2010.06.058
P407
P577
2010-07-22T00:00:00Z