Therapeutic effects of bacteriophage Cpl-1 lysin against Streptococcus pneumoniae endocarditis in rats - Wikidata - wikimedia - TriplyDB

Therapeutic effects of bacteriophage Cpl-1 lysin against Streptococcus pneumoniae endocarditis in rats

Therapeutic effects of bacteriophage Cpl-1 lysin against Streptococcus pneumoniae endocarditis in rats

http://www.wikidata.org/entity/Q34123647

about

Bacteriophage lysins as effective antibacterials Choline Binding Proteins from Streptococcus pneumoniae: A Dual Role as Enzybiotics and Targets for the Design of New Antimicrobials Antimicrobial bacteriophage-derived proteins and therapeutic applications A chimeolysin with extended-spectrum streptococcal host range found by an induced lysis-based rapid screening method Antibacterial gene transfer across the tree of life Bacteriophages and Their Immunological Applications against Infectious Threats.Synergistic Interaction Between Phage Therapy and Antibiotics Clears Pseudomonas Aeruginosa Infection in Endocarditis and Reduces Virulence.Preclinical safety evaluation of intravenously administered SAL200 containing the recombinant phage endolysin SAL-1 as a pharmaceutical ingredient Pharmacokinetics and Tolerance of the Phage Endolysin-Based Candidate Drug SAL200 after a Single Intravenous Administration among Healthy Volunteers.A Novel Chimeric Endolysin with Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus.Bacteriophage endolysins: a novel anti-infective to control Gram-positive pathogens Bacteriophage endolysins as novel antimicrobials.Engineered bacteriophage lysins as novel anti-infectives Recombinant bacteriophage lysins as antibacterials The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice Comparison of the antibacterial properties of phage endolysins SAL-1 and LysK.Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection.Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos.Phage Therapy - Everything Old is New Again Novel approaches to developing new antibiotics for bacterial infections.LysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation Improving the lethal effect of cpl-7, a pneumococcal phage lysozyme with broad bactericidal activity, by inverting the net charge of its cell wall-binding module In vitro characterization of PlySK1249, a novel phage lysin, and assessment of its antibacterial activity in a mouse model of Streptococcus agalactiae bacteremia.Antibiofilm Activities of a Novel Chimeolysin against Streptococcus mutans under Physiological and Cariogenic Conditions.Bacteriophage and their lysins for elimination of infectious bacteria.Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia.Facing antibiotic resistance: Staphylococcus aureus phages as a medical tool.Phage lytic proteins: biotechnological applications beyond clinical antimicrobials.Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent.Bacteriophages and their derivatives for the treatment and control of food-producing animal infections.PEGylating a bacteriophage endolysin inhibits its bactericidal activity.Infection therapy: the problem of drug resistance - and possible solutions.Synthesis of bacteriophage lytic proteins against Streptococcus pneumoniae in the chloroplast of Chlamydomonas reinhardtii.Antibody Guided Molecular Imaging of Infective Endocarditis.Expression of Recombinant pET22b-LysK-Cysteine/Histidine-Dependent Amidohydrolase/Peptidase Bacteriophage Therapeutic Protein in Escherichia coli BL21 (DE3).Intravitreal injection of the chimeric phage endolysin Ply187 protects mice from Staphylococcus aureus endophthalmitis.Exploiting what phage have evolved to control gram-positive pathogens Lytic activity of recombinant bacteriophage phi11 and phi12 endolysins on whole cells and biofilms of Staphylococcus aureus.Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia.Genome analysis of the staphylococcal temperate phage DW2 and functional studies on the endolysin and tail hydrolase.

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Therapeutic effects of bacteriophage Cpl-1 lysin against Streptococcus pneumoniae endocarditis in rats

http://www.wikidata.org/entity/Q34123647

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AAC.49.11.4789-4792.2005

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Antimicrobial Agents and Chemotherapy

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J M Entenza

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J M Loeffler

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P Moreillon

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V A Fischetti

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P2860

Phage lytic enzyme Cpl-1 as a novel antimicrobial for pneumococcal bacteremia

Efficacies of moxifloxacin, ciprofloxacin, and vancomycin against experimental endocarditis due to methicillin-resistant Staphylococcus aureus expressing various degrees of ciprofloxacin resistance

Simulation of amoxicillin pharmacokinetics in humans for the prevention of streptococcal endocarditis in rats.

Streptococcus pneumoniae: epidemiology and patterns of resistance.

Natural history of aortic valve endocarditis in rats

Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin

Synergistic lethal effect of a combination of phage lytic enzymes with different activities on penicillin-sensitive and -resistant Streptococcus pneumoniae strains.

Synergistic killing of Streptococcus pneumoniae with the bacteriophage lytic enzyme Cpl-1 and penicillin or gentamicin depends on the level of penicillin resistance.

Meropenem prevents levofloxacin-induced resistance in penicillin-resistant pneumococci and acts synergistically with levofloxacin in experimental meningitis.

Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model.

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