Scorpion toxins as natural scaffolds for protein engineering
about
Scorpion toxins specific for potassium (K+) channels: a historical overview of peptide bioengineeringProtein design: toward functional metalloenzymesStructure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activityRational engineering of a miniprotein that reproduces the core of the CD4 site interacting with HIV-1 envelope glycoproteinMotions and structural variability within toxins: Implication for their use as scaffolds for protein engineeringElicitation of structure-specific antibodies by epitope scaffoldsHydrolytic catalysis and structural stabilization in a designed metalloproteinConcerted evolution of structure and function in a miniature proteinStable self-assembly of a protein engineering scaffold on gold surfacesDesigning hydrolytic zinc metalloenzymesComputational approaches for rational design of proteins with novel functionalitiesTargeting protein-protein interactions for therapeutic intervention: a challenge for the future.Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide ScaffoldCupricyclins, novel redox-active metallopeptides based on conotoxins scaffold.Influence of active site location on catalytic activity in de novo-designed zinc metalloenzymes.Solution structure of drosomycin, the first inducible antifungal protein from insectsDesign of functional metalloproteins.Protein engineering: security implications. The increasing ability to manipulate protein toxins for hostile purposes has prompted calls for regulationDesign of a zinc-finger hydrolase with a synthetic αββ protein.PredSTP: a highly accurate SVM based model to predict sequential cystine stabilized peptides.Chemical synthesis and structural characterization of the RGD-protein decorsin: a potent inhibitor of platelet aggregation.Selection of carbonic anhydrase variants displayed on phage. Aromatic residues in zinc binding site enhance metal affinity and equilibration kinetics.Alanine substitutions of noncysteine residues in the cysteine-stabilized alphabeta motif.Cyclotides as grafting frameworks for protein engineering and drug design applications.Animal toxins influence voltage-gated sodium channel function.Synthesis and structure-function study about tenecin 1, an antibacterial protein from larvae of Tenebrio molitor.Evaluating the potential of a loop-extended scorpion toxin-like peptide as a protein scaffold.Oxidative folding of cystine-rich peptides vs regioselective cysteine pairing strategies.Cupryphans, metal-binding, redox-active, redesigned conopeptides.Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment.Roles of disulfide bridges in scorpion toxin BmK M1 analyzed by mutagenesis.Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes.Design strategies for the construction of independently folded polypeptide motifs.Molecular Dynamics Simulation Reveals Specific Interaction Sites between Scorpion Toxins and Kv1.2 Channel: Implications for Design of Highly Selective Drugs.Small Scaffolds, Big Potential: Developing Miniature Proteins as Therapeutic Agents.The atomic resolution crystal structure of atratoxin determined by single wavelength anomalous diffraction phasing.Discovery of Peptide Drugs from Natural Sources
P2860
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P2860
Scorpion toxins as natural scaffolds for protein engineering
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Scorpion toxins as natural scaffolds for protein engineering
@ast
Scorpion toxins as natural scaffolds for protein engineering
@en
Scorpion toxins as natural scaffolds for protein engineering
@nl
type
label
Scorpion toxins as natural scaffolds for protein engineering
@ast
Scorpion toxins as natural scaffolds for protein engineering
@en
Scorpion toxins as natural scaffolds for protein engineering
@nl
prefLabel
Scorpion toxins as natural scaffolds for protein engineering
@ast
Scorpion toxins as natural scaffolds for protein engineering
@en
Scorpion toxins as natural scaffolds for protein engineering
@nl
P2093
P2860
P356
P1476
Scorpion toxins as natural scaffolds for protein engineering
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.14.6404
P407
P577
1995-07-01T00:00:00Z