Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs.
about
Lovastatin production by Aspergillus terreus using agro-biomass as substrate in solid state fermentationStructural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase ( Hed KR): Molecular Basis of Stereo- and RegiospecificitiesDifferential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sitesChemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasisImportance of microbial natural products and the need to revitalize their discovery.Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase lower fecundity in the German cockroach: correlation between the effects on fecundity in vivo with the inhibition of enzymatic activity in embryo cells.Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classificationEffect of Temperature-Shift and Temperature-Constant Cultivation on the Monacolin K Biosynthetic Gene Cluster Expression in Monascus sp.Metabolic engineering for the production of natural products.Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities.Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.Allergens/Antigens, toxins and polyketides of important Aspergillus species.Putting fungi to work: harvesting a cornucopia of drugs, toxins, and antibiotics.Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.Three new compounds from Aspergillus terreus PT06-2 grown in a high salt medium.Drugs and drug intermediates from fungi: Striving for greener processes.The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseasesExploring the potential of xenobiotic-metabolising enzymes as biocatalysts: evolving designer catalysts from polyfunctional cytochrome P450 enzymes.Finger millet (Eleusine coracana) - an economically viable source for antihypercholesterolemic metabolites production by Monascus purpureusIsoflavones and phytosterols contained in Xuezhikang capsules modulate cholesterol homeostasis in high-fat diet mice.Genome Shuffling of Mangrove Endophytic Aspergillus luchuensis MERV10 for Improving the Cholesterol-Lowering Agent Lovastatin under Solid State Fermentation.Production of lovastatin and itaconic acid by Aspergillus terreus: a comparative perspective.Microbial production and biomedical applications of lovastatin.Cholesterol, an essential molecule: diverse roles involving cytochrome P450 enzymes.Monascus secondary metabolites: production and biological activity.Mating type genes and cryptic sexuality as tools for genetically manipulating industrial molds.Strategies for mining fungal natural products.The Galpha subunit BCG1, the phospholipase C (BcPLC1) and the calcineurin phosphatase co-ordinately regulate gene expression in the grey mould fungus Botrytis cinerea.The effect of statins on cancer cells--review.Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells.Genetic regulation and manipulation for natural product discovery.The Chemical Composition of Achillea wilhelmsii C. Koch and Its Desirable Effects on Hyperglycemia, Inflammatory Mediators and Hypercholesterolemia as Risk Factors for Cardiometabolic Disease.Natural products from filamentous fungi and production by heterologous expressionNew antifungal compounds from Aspergillus terreus isolated from desert soil.Monascus-fermented red mold rice exhibits cytotoxic effect and induces apoptosis on human breast cancer cells.Complete Genome Sequence of Soil Fungus Aspergillus terreus (KM017963), a Potent Lovastatin Producer.Assessment of monacolin in the fermented products using Monascus purpureus FTC5391Reconstruction of the central carbon metabolism of Aspergillus niger.Lack of the COMPASS Component Ccl1 Reduces H3K4 Trimethylation Levels and Affects Transcription of Secondary Metabolite Genes in Two Plant-Pathogenic Fusarium Species.Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
P2860
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P2860
Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@ast
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@en
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@nl
type
label
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@ast
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@en
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@nl
prefLabel
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@ast
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@en
Biosynthesis and biotechnologi ...... se cholesterol-lowering drugs.
@nl
P1476
Biosynthesis and biotechnologi ...... ese cholesterol-lowering drugs
@en
P2093
P2888
P304
P356
10.1007/S00253-002-0932-9
P407
P577
2002-02-14T00:00:00Z
P5875
P6179
1012833744