Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling. - Wikidata - wikimedia - TriplyDB

Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling.

Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling.

http://www.wikidata.org/entity/Q34124356

about

Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line Preadministration of High-Dose Salicylates, Suppressors of NF- B Activation, May Increase the Chemosensitivity of Many Cancers: An Example of Proapoptotic Signal Modulation Therapy Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1.Disrupting P-glycoprotein function in clinical settings: what can we learn from the fundamental aspects of this transporter?Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cells Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model Neuroinflammation activates Mdr1b efflux transport through NFkappaB: promoter analysis in BBB endothelia Low intensity ultrasound promotes the sensitivity of rat brain glioma to Doxorubicin by down-regulating the expressions of p-glucoprotein and multidrug resistance protein 1 in vitro and in vivo.Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells.Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells.Multidrug resistance 1 gene polymorphisms may determine Crohn's disease behavior in patients from Rio de Janeiro.Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma.Transferrin-targeted polymeric micelles co-loaded with curcumin and paclitaxel: efficient killing of paclitaxel-resistant cancer cells.Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation.Pro-inflammatory cytokine regulation of P-glycoprotein in the developing blood-brain barrier.Metformin combined with p38 MAPK inhibitor improves cisplatin sensitivity in cisplatin‑resistant ovarian cancer.PIK3CA and PIK3CB expression and relationship with multidrug resistance in colorectal carcinoma.Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway.β-escin reverses multidrug resistance through inhibition of the GSK3β/β-catenin pathway in cholangiocarcinoma Forced expression of heat shock protein 27 (Hsp27) reverses P-glycoprotein (ABCB1)-mediated drug efflux and MDR1 gene expression in Adriamycin-resistant human breast cancer cells The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias.The human P-glycoprotein transporter enhances the type I interferon response to Listeria monocytogenes infection Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity.Mitochondrial roles and cytoprotection in chronic liver injury Role of nuclear factor-kappa B in melanoma.Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells.Mechanisms of doxorubicin resistance in hepatocellular carcinoma Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity Multifactorial nature of hepatocellular carcinoma drug resistance: could plant polyphenols be helpful?Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunities Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability.NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.ABC transporters as molecular effectors of pancreatic oncogenic pathways: the Hedgehog-GLI model.Overcoming platinum drug resistance with copper-lowering agents.Signal transduction pathways and transcriptional mechanisms of ABCB1/Pgp-mediated multiple drug resistance in human cancer cells.MDR1 will play a key role in pharmacokinetic changes under hypoxia at high altitude and its potential regulatory networks.Visfatin mediates doxorubicin resistance in human colorectal cancer cells via up regulation of multidrug resistance 1 (MDR1).Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.

P2860

Q21134144-EC1AF603-1255-4D88-B198-65D6BFC48AD9 Q22299231-2D7EEC1A-3ACB-4997-892B-D101C558716A Q24634572-23D8348D-A6BB-4A5E-90A0-8FBEB0ED1923 Q27335381-9F87E73A-7623-4929-A8F7-28D2FDF87462 Q28069761-13A04E6A-6BCF-4E80-BEF7-5B3B50751348 Q28535383-66A0B80C-DF2A-434A-A8B2-5AE71E02FAD5 Q28573518-6C24A18C-BF2F-4176-AA86-47EAA9D3C50A Q28578682-43E17163-4F9C-453C-9B1E-15D4C26D269B Q30450941-6ACDF9F5-8339-4F4E-A897-F3D22285144C Q33394070-51A1946E-CE5A-4901-9097-D5A4BF69155A Q33399904-E6472E24-5508-422F-9265-7DFE8F2EE77E Q33574823-E3FC071D-E54F-4260-B227-06798BA634EE Q33904328-E6006A40-FBD0-4246-BA5E-EC57425E460F Q34047136-9C7DC5B3-91E1-4746-9154-410066B8678C Q34148357-306B7BE9-9716-432F-9ED1-46FCBCD1C531 Q34413660-7787BD8C-5247-42AE-86C7-030B95514447 Q34426894-17EA6E87-F57D-4FE9-AC09-622ED2D8528E Q34732954-8271C30D-E20C-4C96-9263-3AED6D8DB1CA Q34888009-823BAAAD-CC0C-4356-9EE5-D3AD7786F489 Q35012043-8242E84F-DB12-4058-8E26-F7B8212C4607 Q35312427-297DCE27-C906-4D95-A5A8-A9D25B20E5DF Q35552693-55EEB99A-9A50-4377-9A97-6AD27CEEEF93 Q35609414-8A4931AF-F67C-408B-906C-B3BFFC4353B6 Q35748395-ECC8D9C9-71A9-4384-9195-C24664915F85 Q36055801-A1269EA8-7B7F-47C9-A200-36B9DE44A551 Q36178379-B13844AE-F2B9-40E5-9105-34995AA7B6F4 Q36206219-F6030D0B-C0F9-4A9D-A0C1-8517F3DA6ADC Q36687760-AB82C58E-BC50-4032-A63C-ECE607E155B9 Q36800903-E1D5E594-D2A0-4D8B-B93F-17D02411110A Q36804306-F68955F6-928F-403B-96ED-DE318757A8B7 Q36899877-5AFAEFB6-835B-49A0-8E4B-5D952541A880 Q36960756-576DBF82-7E15-4220-935D-3B656B10DD07 Q37184967-7F868DA4-3D3F-43E7-B561-55EC0506CEB3 Q37638021-2143EA2A-D6AD-4EA6-A551-F139DCB9F731 Q37718060-8CC99059-A14A-4C22-9AB2-963FAC147019 Q37727299-211176BE-C907-4C16-AE73-1FB4BEE57DEA Q38011895-94C80343-F066-4867-9D2E-AC7EB6F44F40 Q38339659-EB127033-D466-4374-A134-74C9CB06C53B Q38698485-5D511889-A0ED-4A97-BC09-F97CA6C74A43 Q38769105-1EE0103A-CADF-4E19-B8D7-2A1488966FA2

P2860

Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling.

http://www.wikidata.org/entity/Q34124356

description

2002 nî lūn-bûn

@nan

2002 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի մարտին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@ast

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@en

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@nl

type

label

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@ast

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@en

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@nl

prefLabel

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@ast

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@en

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@nl

P1433

Q34124356-3F49FCDF-7E05-4F1F-BFA7-D466F4C810BC

P1476

Q34124356-68B7A95F-1169-4564-9BC4-D2610DA4B9FB

P2093

Q34124356-047F2CB4-187F-4FD4-8C82-3B6139FD5C0A

Q34124356-5D84845B-081F-460A-B908-800E7C116C97

Q34124356-A27B0A53-CFA7-43D1-A045-FABE77C9019D

Q34124356-A33FC0C3-5810-47E8-A587-243F9AD5C7EC

Q34124356-C4E2A4A6-3FF2-440F-855D-EA3A2C0CC5E3

Q34124356-F1C8A341-C8C9-464C-85F4-4B21B2ECABCF

Q34124356-F2A9145B-4412-4A87-B8D4-CA09306FA2ED

P2860

Q34124356-0404BA45-0177-41F4-A90B-D842E95034CD

Q34124356-05025919-296B-48E6-B3CF-ED374DE76832

Q34124356-07D61954-60F9-4B4A-802E-C7D27AE1BBEB

Q34124356-09771DDD-F977-4D4B-B1AF-41280A9686CA

Q34124356-11505DDC-4BCA-4E48-B431-405DD3E4EC03

Q34124356-120853FD-7151-40C4-BE8F-ACCD2FC0CF0C

Q34124356-174EA6B8-8CAC-4B51-B350-068F7EE1224E

Q34124356-1DD78149-E338-41F8-80D1-2DCA5D6772BA

Q34124356-1F6C1665-2D28-43A5-8652-939A9BE377A4

Q34124356-3404E92D-0336-490E-9890-6A7E0C7CA2D1

P2888

Q34124356-335985B5-D600-4122-866E-DC5D521AFE78

P304

Q34124356-B0D14C8A-EEF1-40FE-BA32-063708790DE9

P31

Q34124356-B9F76F38-BBB6-404E-B98D-87DCA19F4868

P356

Q34124356-147238C4-DB6C-4C0A-951E-25C263575341

P407

Q34124356-877A15F2-F36E-49E4-8259-6C55C9FF790B

P433

Q34124356-5FD16997-1003-453E-8409-1794C36D1144

P478

Q34124356-73194F12-C250-44CC-9835-DEE12B970B46

P577

Q34124356-7F893FC1-A6F3-47AE-8DF5-964D1DD54D4A

P5875

Q34124356-4F5147A6-2006-428E-AB01-3AEE7FF7E524

P6179

Q34124356-3DBB3FE7-BD5B-4C6E-AB6F-2ED56DAB0BC7

P698

Q34124356-99572580-8E7B-4A3E-9A96-5A5471BA1908

P921

Q34124356-4134D487-649F-4EB7-A778-15660F085C8D

P356

P1433

P1476

Induction of human MDR1 gene e ...... activate NF-kappaB signaling.

@en

P2093

Gordon B Mills

http://www.w3.org/2001/XMLSchema#string

Hitoshi Unate

http://www.w3.org/2001/XMLSchema#string

Macus Tien Kuo

http://www.w3.org/2001/XMLSchema#string

Shigeru Tatebe

http://www.w3.org/2001/XMLSchema#string

Yen-chiu Lin-Lee

http://www.w3.org/2001/XMLSchema#string

Yingjie Wei

http://www.w3.org/2001/XMLSchema#string

Zesheng Liu

http://www.w3.org/2001/XMLSchema#string

P2860

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

Cell signaling by receptor tyrosine kinases

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

P2888

P304

1945-1954

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1205117

http://www.w3.org/2001/XMLSchema#string

P407

P433

13

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P577

2002-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11407751

http://www.w3.org/2001/XMLSchema#string

P6179

1030359216

http://www.w3.org/2001/XMLSchema#string

P698

11960367

http://www.w3.org/2001/XMLSchema#string

P921