Kinetic analysis of phasic inhibition of neuronal sodium currents by lidocaine and bupivacaine
about
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channelsState-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents.At therapeutic concentration bupivacaine causes neuromuscular blockade and enhances rocuronium-induced blockade.Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations.Subtype-selective targeting of voltage-gated sodium channels.Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence.State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution.Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics.Irreversible inhibition of sodium current and batrachotoxin binding by a photoaffinity-derivatized local anesthetic.Direct inhibition of the actomyosin motility by local anesthetics in vitro.A method for estimation of drug affinity constants to the open conformational state of calcium channels.Lidocaine selectively blocks abnormal impulses arising from noninactivating Na channels.
P2860
Q28379121-6EAF3489-DBB3-4795-8A57-D54C84A05B37Q30866710-0635C60F-B1C4-4A5C-B047-D9DCA9496331Q36005028-17D2BF87-3516-419D-9341-1EF91DC06749Q36558186-C038BF19-EA60-498B-9B04-0AEFDEFFDBF5Q37618893-02A2B07C-BF8C-4A55-A030-40C69C986413Q39631657-9AD2EBF9-6470-477E-91D7-1E71D1417E3FQ40923244-899EE321-B20B-4684-BB23-4D1E40382D8AQ41668278-61C5D583-821D-43CF-917E-FD511100E8E2Q41908034-D11A7F34-34FD-4C21-B8FB-D6C5F13B7F3EQ42184420-7281115E-7E19-447A-8CEF-176F1D8FC068Q42583911-9BD9885A-77FA-44D7-978E-8350867EBBA8Q43585277-2ABF3DB0-F167-4C85-8E2D-453F5044FE3C
P2860
Kinetic analysis of phasic inhibition of neuronal sodium currents by lidocaine and bupivacaine
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@ast
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@en
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@nl
type
label
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@ast
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@en
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@nl
prefLabel
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@ast
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@en
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@nl
P2860
P1433
P1476
Kinetic analysis of phasic inh ...... s by lidocaine and bupivacaine
@en
P2093
D M Chernoff
P2860
P356
10.1016/S0006-3495(90)82353-5
P407
P577
1990-07-01T00:00:00Z