Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes. - Wikidata - wikimedia - TriplyDB

Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes.

Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes.

http://www.wikidata.org/entity/Q34126610

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Age-related decrease of meiotic cohesins in human oocytes Human aneuploidy: mechanisms and new insights into an age-old problem Oocyte Maturation and Development Oocyte development, meiosis and aneuploidy Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Sister chromatid segregation in meiosis II: deprotection through phosphorylation Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes Meiosis and maternal aging: insights from aneuploid oocytes and trisomy births Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis Aurora kinase-A regulates microtubule organizing center (MTOC) localization, chromosome dynamics, and histone-H3 phosphorylation in mouse oocytes Bora regulates meiotic spindle assembly and cell cycle during mouse oocyte meiosis Meikin is a conserved regulator of meiosis-I-specific kinetochore function Mutant Cohesin in Premature Ovarian Failure Cohesion fatigue induces chromatid separation in cells delayed at metaphase.Premature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytes Bivalent separation into univalents precedes age-related meiosis I errors in oocytes.DNA damage response during mouse oocyte maturation.Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1 Kinetochore microtubule establishment is defective in oocytes from aged mice Effect of women's age on embryo morphology, cleavage rate and competence-A multicenter cohort study.Age-related increase in aneuploidy and alteration of gene expression in mouse first polar bodies Meiosis I in Xenopus oocytes is not error-prone despite lacking spindle assembly checkpoint.Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.Arrested human embryos are more likely to have abnormal chromosomes than developing embryos from women of advanced maternal age.Examining variation in recombination levels in the human female: a test of the production-line hypothesis Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.The association of low socioeconomic status and the risk of having a child with Down syndrome: a report from the National Down Syndrome Project.A single bivalent efficiently inhibits cyclin B1 degradation and polar body extrusion in mouse oocytes indicating robust SAC during female meiosis I.Rejuvenation of meiotic cohesion in oocytes during prophase I is required for chiasma maintenance and accurate chromosome segregation.Deterioration without replenishment--the misery of oocyte cohesin.Mechanisms of aneuploidy.DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.Meiosis: cohesin's hidden role in the checkpoint revealed.Altered cohesin gene dosage affects Mammalian meiotic chromosome structure and behavior.Nucleosome assembly proteins get SET to defeat the guardian of chromosome cohesion Trisomic pregnancy and elevated FSH: implications for the oocyte pool hypothesis.Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice

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Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes.

http://www.wikidata.org/entity/Q34126610

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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name

Evidence that weakened centrom ...... related aneuploidy in oocytes.

@ast

Evidence that weakened centrom ...... related aneuploidy in oocytes.

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Evidence that weakened centrom ...... related aneuploidy in oocytes.

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type

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Evidence that weakened centrom ...... related aneuploidy in oocytes.

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Evidence that weakened centrom ...... related aneuploidy in oocytes.

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Evidence that weakened centrom ...... related aneuploidy in oocytes.

@nl

prefLabel

Evidence that weakened centrom ...... related aneuploidy in oocytes.

@ast

Evidence that weakened centrom ...... related aneuploidy in oocytes.

@en

Evidence that weakened centrom ...... related aneuploidy in oocytes.

@nl

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J.CUB.2010.06.069

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Current Biology

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Evidence that weakened centrom ...... -related aneuploidy in oocytes

@en

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Francesca E Duncan

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Michael A Lampson

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Richard M Schultz

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Teresa Chiang

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P2860

Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I.

To err (meiotically) is human: the genesis of human aneuploidy

Maternal aging and chromosomal abnormalities: new data drawn from in vitro unfertilized human oocytes.

Aging predisposes oocytes to meiotic nondisjunction when the cohesin subunit SMC1 is reduced.

The molecular basis of sister-chromatid cohesion.

Cohesin Rec8 is required for reductional chromosome segregation at meiosis.

Sister chromatid cohesion along arms and at centromeres.

First-meiotic-division nondisjunction in human oocytes.

Effect of meiotic recombination on the production of aneuploid gametes in humans.

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

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