Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. - Wikidata - wikimedia - TriplyDB

Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

http://www.wikidata.org/entity/Q34128674

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Histone methyltransferases: novel targets for tumor and developmental defects New insights into establishment and maintenance of DNA methylation imprints in mammals Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation Flavin-dependent enzymes in cancer prevention Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b The Methyltransferase NSD3 Has Chromatin-binding Motifs, PHD5-C5HCH, That Are Distinct from Other NSD (Nuclear Receptor SET Domain) Family Members in Their Histone H3 Recognition Structural insight into substrate recognition by histone demethylase LSD2/KDM1b Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells KDM1 class flavin-dependent protein lysine demethylases Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism.Brain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor.Modulation of chromatin remodelling induced by the freshwater cyanotoxin cylindrospermopsin in human intestinal caco-2 cells.Transcriptional regulation of the albumin gene depends on the removal of histone methylation marks by the FAD-dependent monoamine oxidase lysine-specific demethylase 1 in HepG2 human hepatocarcinoma cells HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators Regulation of histone H3K4 methylation in brain development and disease.Small-molecular modulators of cancer-associated epigenetic mechanisms.Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity.In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.Transcription driven somatic DNA methylation within the imprinted Gnas cluster Balancing histone methylation activities in psychiatric disorders.Dynamic CpG island methylation landscape in oocytes and preimplantation embryos A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing.Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties.Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2 Targeting protein lysine methylation and demethylation in cancers.Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation Genomic imprinting: recognition and marking of imprinted loci.Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape Hepatic ontogeny and tissue distribution of mRNAs of epigenetic modifiers in mice using RNA-sequencing.The LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback Loop Dynamic changes in histone modifications precede de novo DNA methylation in oocytes.Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer.MiR-215 Is Induced Post-transcriptionally via HIF-Drosha Complex and Mediates Glioma-Initiating Cell Adaptation to Hypoxia by Targeting KDM1B.

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Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

http://www.wikidata.org/entity/Q34128674

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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Human LSD2/KDM1b/AOF1 regulate ...... ntragenic H3K4me2 methylation.

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J.MOLCEL.2010.07.008

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Human LSD2/KDM1b/AOF1 regulate ...... intragenic H3K4me2 methylation

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Andrew J Barbera

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Christine Lian

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Dongmei Cheng

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Fei Lan

http://www.w3.org/2001/XMLSchema#string

Guangchao Sui

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Guo-Cheng Yuan

http://www.w3.org/2001/XMLSchema#string

Junmin Peng

http://www.w3.org/2001/XMLSchema#string

Michael Rutenberg

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Qing Bi

http://www.w3.org/2001/XMLSchema#string

Rui Fang

http://www.w3.org/2001/XMLSchema#string

P2860

Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors

Translating the Histone Code

The Sequence of the Human Genome

Insights into the function of the human P-TEFb component CDK9 in the regulation of chromatin modifications and co-transcriptional mRNA processing

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

High-resolution profiling of histone methylations in the human genome

The language of covalent histone modifications

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.

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222-233

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10.1016/J.MOLCEL.2010.07.008

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39

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2010-07-01T00:00:00Z

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20670891

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