A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis - Wikidata - wikimedia - TriplyDB

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

http://www.wikidata.org/entity/Q34131187

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An outline of necrosome triggers Interleukin-1 Family Cytokines in Liver Diseases Death in the fast lane: what's next for necroptosis?Role of necroptosis in the pathogenesis of solid organ injury The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.Molecular Pathogenesis of NASH Questions and controversies: the role of necroptosis in liver disease Targeting Cell Death and Sterile Inflammation Loop for the Treatment of Nonalcoholic Steatohepatitis miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.Death Receptor-Mediated Cell Death and Proinflammatory Signaling in Nonalcoholic Steatohepatitis.The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis.Cell death and cell death responses in liver disease: mechanisms and clinical relevance Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.High-mobility group protein box1 expression correlates with peritumoral macrophage infiltration and unfavorable prognosis in patients with hepatocellular carcinoma and cirrhosis Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death.Activation of necroptosis in human and experimental cholestasis.Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair Immunoregulation by lipids during the development of non-alcoholic steatohepatitis.Hepatocytes in liver injury: Victim, bystander, or accomplice in progressive fibrosis?Host homeostatic responses to alcohol-induced cellular stress in animal models of alcoholic liver disease.Pathophysiological mechanisms and therapeutic potentials of macrophages in non-alcoholic steatohepatitis.TNFα in liver fibrosis.The in vivo evidence for regulated necrosis.The Inflammatory Signal Adaptor RIPK3: Functions Beyond Necroptosis.Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.Necroptosis: Mechanisms and Relevance to Disease.Necroptosis in Nonalcoholic Steatohepatitis.Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis.Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-κB.Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury Acetaminophen knocks on death's door and receptor interacting protein 1 kinase answers.Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death.Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.The JNK Signaling Pathway in Renal Fibrosis.Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.miRNA-21 ablation protects against liver injury and necroptosis in cholestasis.Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression.

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A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

http://www.wikidata.org/entity/Q34131187

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

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2014年論文

@zh-tw

2014年论文

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name

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@ast

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@en

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@nl

type

label

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@ast

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@en

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@nl

prefLabel

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@ast

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

@en

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

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EMBO Molecular Medicine

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A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

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P2093

Ali Canbay

http://www.w3.org/2001/XMLSchema#string

Anne Theres Schneider

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Christian Trautwein

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Christiane Koppe

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Christoph Roderburg

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David Vargas Cardenas

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Florian Reisinger

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Frank Tacke

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Helen Louise Reeves

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Jérémie Gautheron

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P2860

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

Regulation of lipid stores and metabolism by lipophagy

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

P304

1062-1074

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scholarly article

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10.15252/EMMM.201403856

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P433

8

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6

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Mathias Heikenwalder

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2014-06-24T00:00:00Z

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263432184

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24963148

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P921

Steatohepatitis

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4154133

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