The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.
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Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant TherapyNuclear receptor LRH-1 induces the reproductive neuropeptide kisspeptin in the hypothalamus.Oxysterols and their cellular effectors.The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells.From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.A screening cascade to identify ERβ ligands.Cholesterol and breast cancer pathophysiology.27-Hydroxycholesterol: the first identified endogenous SERMMinireview: nuclear receptor regulation of osteoclast and bone remodeling.The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.A tricistronic human adrenodoxin reductase-adrenodoxin-cytochrome P450 27A1 vector system for substrate hydroxylation in Escherichia coliThe oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptorsExercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancerMolecular mechanisms of ursodeoxycholic acid toxicity & side effects: ursodeoxycholic acid freezes regeneration & induces hibernation mode.Re-adopting classical nuclear receptors by cholesterol metabolites.The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosisThe molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.A High-Cholesterol Diet Increases 27-Hydroxycholesterol and Modifies Estrogen Receptor Expression and Neurodegeneration in Rabbit Hippocampus.The Contribution of Cholesterol and Its Metabolites to the Pathophysiology of Breast CancerMicroRNA: a connecting road between apoptosis and cholesterol metabolism.The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.Detection of Endogenous Selective Estrogen Receptor Modulators such as 27-Hydroxycholesterol.The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer.27-Hydroxycholesterol, an endogenous selective estrogen receptor modulator.27-Hydroxycholesterol stimulates cell proliferation and resistance to docetaxel-induced apoptosis in prostate epithelial cells.
P2860
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P2860
The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The endogenous selective estro ...... regulator of bone homeostasis.
@ast
The endogenous selective estro ...... regulator of bone homeostasis.
@en
The endogenous selective estro ...... regulator of bone homeostasis.
@nl
type
label
The endogenous selective estro ...... regulator of bone homeostasis.
@ast
The endogenous selective estro ...... regulator of bone homeostasis.
@en
The endogenous selective estro ...... regulator of bone homeostasis.
@nl
prefLabel
The endogenous selective estro ...... regulator of bone homeostasis.
@ast
The endogenous selective estro ...... regulator of bone homeostasis.
@en
The endogenous selective estro ...... regulator of bone homeostasis.
@nl
P2093
P2860
P356
P1433
P1476
The endogenous selective estro ...... regulator of bone homeostasis
@en
P2093
Carolyn D DuSell
Diane Gesty-Palmer
Donald P McDonnell
Jennifer Abdo
Michihisa Umetani
Norman B Javitt
Ulrike I Mödder
Xiaojuan Wang
P2860
P304
P356
10.1210/EN.2010-0080
P407
P577
2010-05-25T00:00:00Z