MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease
about
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in miceMultimodal MRI Evaluation of the MitoPark Mouse Model of Parkinson's DiseaseMitochondrial dysfunction in neurodegenerative diseasesL-Dopa induced dyskinesias in Parkinsonian mice: Disease severity or L-Dopa historyDopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease.Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivoTetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM.High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratioImpaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's diseaseCognitive dysfunction precedes the onset of motor symptoms in the MitoPark mouse model of Parkinson's diseaseChronic L-DOPA induces hyperactivity, normalization of gait and dyskinetic behavior in MitoPark miceAnimal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons.Modeling mitochondrial dysfunctions in the brain: from mice to men.Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons.PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark miceMitochondrial retrograde signaling regulates neuronal functionMitochondrial biogenesis: a therapeutic target for neurodevelopmental disorders and neurodegenerative diseasesLmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neuronsGlial cell line-derived neurotrophic factor partially ameliorates motor symptoms without slowing neurodegeneration in mice with respiratory chain-deficient dopamine neurons.The impact of mitochondrial DNA and nuclear genes related to mitochondrial functioning on the risk of Parkinson's disease.Dopamine: A Modulator of Circadian Rhythms in the Central Nervous System.Parkinson's disease mouse models in translational research.Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease.Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice.Altered glutamate release in the dorsal striatum of the MitoPark mouse model of Parkinson's disease.Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.Mice lacking the Parkinson's related GPR37/PAEL receptor show non-motor behavioral phenotypes: age and gender effect.The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms.GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice.Overexpression of Wild-Type Human Alpha-Synuclein Causes Metabolism Abnormalities in Thy1-aSYN Transgenic MiceRole of Mitochondrial Dysfunction in Degenerative Brain Diseases, an Overview
P2860
Q27308060-000A5910-6E40-4E2A-998F-DEDD2A4AB8C8Q27316725-B0B6831D-9EFA-43CA-BE71-15764397FE04Q28387647-6D1712A2-0BAC-4CF9-A3DE-10CA08F5EFC7Q28602694-3B51BBCE-006C-4A3C-B00E-D6025C8210B4Q30372768-EA8ACF5F-F355-4FC2-98DE-CF0AE97C5505Q30503280-DE8DE11A-C313-48D3-BDC0-384F789629DAQ33698136-7ED07991-10A6-4281-B5F1-AB178419BB10Q34359196-299114A5-6612-412D-8AE7-24B4AE9197A2Q34682391-E51A7D33-A622-447C-AC32-809C0EC6E5FEQ34970932-DD9527FE-CA12-4E29-B1DC-2FF6650D9EBDQ35509519-6C8ED276-891C-41BD-83C7-637377D6BA71Q35589979-443E9937-7071-40FB-8438-C04A5898B8C0Q35750220-8C4ECE9C-9B2F-441D-84CA-BD4830936D65Q35754400-1ECAFA7F-B795-4947-A3C0-B2A8345BD01FQ35852144-2B75A944-22E5-451D-AF20-8F23A9824373Q36218704-497FB052-A621-403A-BE7F-3DF3F01748B4Q36268449-4E5D456C-016E-4823-B3F3-6B13584F9CAEQ36771650-A8ABB5F8-1E67-4DB9-920D-D6090FD815ACQ37142863-55D24068-7A83-46AA-8E38-EA0159373D7BQ37466357-DC5CAC21-26D0-40F7-9401-B34E71FB6CA8Q37583410-B1E973E0-F160-459B-9702-262F26BB9329Q37733707-DD13A3BE-3736-4A25-9695-35E795D9D718Q37874160-6B9313A9-85BC-4A84-9DB1-7FF7325457ECQ38708951-52DE7971-3933-424A-A80F-0B8BE80DC2D7Q38855994-CBCCC105-00CC-46D4-AE2E-80992F41C949Q42499434-60C2354C-DBD6-4F61-BFBB-3FCC0ADF9E99Q42510777-4F50EBC0-C8CA-4252-95E6-67E26EAADF96Q48031082-F0A1CEEB-A26F-4936-A21C-CB4D3064B0ECQ49823902-6DAA0EA3-6CD0-4306-97E5-CF19CF14690CQ52721898-695F1D35-1F92-423B-BFAC-053E672BB483Q58586715-DB8CF138-F237-495B-97E2-2BBDDD074F14Q58708614-BBDB2E83-B0F1-40D6-AFF0-321081666386
P2860
MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@ast
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@en
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@nl
type
label
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@ast
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@en
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@nl
prefLabel
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@ast
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@en
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@nl
P2093
P2860
P1476
MitoPark mice mirror the slow ...... esponse in Parkinson's disease
@en
P2093
E Lindqvist
N-G Larsson
T Yoshitake
P2860
P304
P356
10.1111/J.1601-183X.2009.00542.X
P407
P577
2009-10-07T00:00:00Z