Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation - Wikidata - wikimedia - TriplyDB

Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation

Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation

http://www.wikidata.org/entity/Q34133279

about

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease Mitochondrial gene replacement in primate offspring and embryonic stem cells.Modulating mitochondrial quality in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants Do mtDNA deletions drive premature aging in mtDNA mutator mice?Segregation of Naturally Occurring Mitochondrial DNA Variants in a Mini-Pig Model Chromosome transfer in mature oocytes.The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging.Transmission of mitochondrial DNA diseases and ways to prevent them.Reverse genetic studies of mitochondrial DNA-based diseases using a mouse model.Mitochondrial ATP synthase: architecture, function and pathology.Mitochondrial replacement: from basic research to assisted reproductive technology portfolio tool-technicalities and possible risks.Mitochondrial replacement therapy in reproductive medicine.Social and ethical issues in mitochondrial donation.Implications of human evolution and admixture for mitochondrial replacement therapy.Mitochondrial DNA mutations in mutator mice confer respiration defects and B-cell lymphoma development.Poor correlations in the levels of pathogenic mitochondrial DNA mutations in polar bodies versus oocytes and blastomeres in humans.Mitochondria-related male infertility.Concise reviews: Assisted reproductive technologies to prevent transmission of mitochondrial DNA disease Mitochondrial DNA disease: new options for prevention.Deletion-mutant mtDNA increases in somatic tissues but decreases in female germ cells with age.Mitochondrial content is central to nuclear gene expression: Profound implications for human health.Attitudes toward prevention of mtDNA-related diseases through oocyte mitochondrial replacement therapy.Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse.Improvement of embryonic development and production of offspring by transferring meiosis-II chromosomes of senescent mouse oocytes into cytoplasts of young mouse oocytes Mitochondrial DNA with a large-scale deletion causes two distinct mitochondrial disease phenotypes in mice.Progress and prospects: gene therapy for mitochondrial DNA disease.Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.Mitochondrial DNA mutations and aging: devils in the details?Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene Clinical and ethical implications of mitochondrial gene transfer.Mitochondrial function and mitochondrial DNA maintenance with advancing age.Polar bodies in assisted reproductive technology: current progress and future perspectives.Mutations causing mitochondrial disease: What is new and what challenges remain?Novel reproductive technologies to prevent mitochondrial disease.Intra-individual purifying selection on mitochondrial DNA variants during human oogenesis.Mitochondrial Replacement Therapy: Are Mito-nuclear Interactions Likely To Be a Problem?Avoiding transgenerational risks of mitochondrial DNA disorders: a morally acceptable reason for sex selection?Aberrant nucleo-cytoplasmic cross-talk results in donor cell mtDNA persistence in cloned embryos.Do somatic mitochondrial DNA mutations contribute to Parkinson's disease?

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P2860

Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation

http://www.wikidata.org/entity/Q34133279

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Gene therapy for progeny of mi ...... DNA by nuclear transplantation

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Gene therapy for progeny of mi ...... DNA by nuclear transplantation

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Gene therapy for progeny of mi ...... DNA by nuclear transplantation

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type

label

Gene therapy for progeny of mi ...... DNA by nuclear transplantation

@ast

Gene therapy for progeny of mi ...... DNA by nuclear transplantation

@en

Gene therapy for progeny of mi ...... DNA by nuclear transplantation

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Gene therapy for progeny of mi ...... DNA by nuclear transplantation

@ast

Gene therapy for progeny of mi ...... DNA by nuclear transplantation

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Gene therapy for progeny of mi ...... DNA by nuclear transplantation

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PNAS.0506197102

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Gene therapy for progeny of mi ...... DNA by nuclear transplantation

@en

P2093

Akitsugu Sato

http://www.w3.org/2001/XMLSchema#string

Hiromichi Yonekawa

http://www.w3.org/2001/XMLSchema#string

Jun-Ichi Hayashi

http://www.w3.org/2001/XMLSchema#string

Kaori Ishikawa

http://www.w3.org/2001/XMLSchema#string

Kazuto Nakada

http://www.w3.org/2001/XMLSchema#string

Shin-Ichi Inoue

http://www.w3.org/2001/XMLSchema#string

Tomohiro Kono

http://www.w3.org/2001/XMLSchema#string

P2860

Maternal inheritance of mouse mtDNA in interspecific hybrids: segregation of the leaked paternal mtDNA followed by the prevention of subsequent paternal leakage

Mitochondrial diseases in man and mouse

Rare creation of recombinant mtDNA haplotypes in mammalian tissues.

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation.

Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis

Mitochondrial disorders: genetics, counseling, prenatal diagnosis and reproductive options.

Evidence from human oocytes for a genetic bottleneck in an mtDNA disease.

Selective and continuous elimination of mitochondria microinjected into mouse eggs from spermatids, but not from liver cells, occurs throughout embryogenesis

In vivo interaction between mitochondria carrying mtDNAs from different mouse species

Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles.

P304

16765-16770

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scholarly article

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10.1073/PNAS.0506197102

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P407

P433

46

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P478

102

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2005-11-07T00:00:00Z

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7492210

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16275929

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1283814

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