Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.
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P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2An essential role of the Jak-2/STAT-3/cytosolic phospholipase A(2) axis in platelet-derived growth factor BB-induced vascular smooth muscle cell motilityIL-1beta enhances beta2-adrenergic receptor expression in human airway epithelial cells by activating PKC.The IL-1 receptor and Rho directly associate to drive cell activation in inflammation.Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels in murine mast cells by recombinant stem cell factorcPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loopCytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway.The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cellsEicosanoid profiling in an orthotopic model of lung cancer progression by mass spectrometry demonstrates selective production of leukotrienes by inflammatory cells of the microenvironment.Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes.Cytosolic domain of the type I interleukin-1 receptor spontaneously recruits signaling molecules to activate a proinflammatory gene85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells.Differential stimulation of cytosolic phospholipase A2 by bradykinin in human cystic fibrosis cell lines.Interleukin-1-induced growth inhibition of human melanoma cells. Interleukin-1-induced antizyme expression is responsible for ornithine decarboxylase activity down-regulation.Expression of both P1 and P2 purine receptor genes by human articular chondrocytes and profile of ligand-mediated prostaglandin E2 release.G-protein-gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases.Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death.Cytosolic phospholipase A2 is an effector of Jak/STAT signaling and is involved in platelet-derived growth factor BB-induced growth in vascular smooth muscle cells.A requirement for calcium-independent phospholipase A2 in thrombin-induced arachidonic acid release and growth in vascular smooth muscle cells.STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility.Fibroblast growth factor-2 is a downstream mediator of phosphatidylinositol 3-kinase-Akt signaling in 14,15-epoxyeicosatrienoic acid-induced angiogenesis.Cyclic GMP and cGMP-binding phosphodiesterase are required for interleukin-1-induced nitric oxide synthesis in human articular chondrocytes.Distribution of secretory phospholipase A2 XIIA in the brain and its role in lipid metabolism and cognition.Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells.
P2860
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P2860
Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@ast
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@en
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@nl
type
label
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@ast
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@en
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@nl
prefLabel
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@ast
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@en
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@nl
P2093
P2860
P356
P1476
Interleukin 1 alpha causes rap ...... lation in rat mesangial cells.
@en
P2093
M Konieczkowski
R A Nemenoff
P2860
P304
P356
10.1172/JCI117076
P407
P577
1994-03-01T00:00:00Z