Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy. - Wikidata - wikimedia - TriplyDB

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

http://www.wikidata.org/entity/Q34135239

about

Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells Choline and betaine intake and risk of breast cancer among post-menopausal women Dietary choline and betaine and the risk of distal colorectal adenoma in women Choline Metabolism Alteration: A Focus on Ovarian Cancer The human plasma lipidome Choline metabolism-based molecular diagnosis of cancer: an update The E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in mice Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation Choline kinase and its function Highly specific antibodies for co-detection of human choline kinase α1 and α2 isoforms Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells Metformin Decouples Phospholipid Metabolism in Breast Cancer Cells Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products.Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.The response of RIF-1 fibrosarcomas to the vascular-disrupting agent ZD6126 assessed by in vivo and ex vivo 1H magnetic resonance spectroscopy.Restricted water diffusibility as measured by diffusion-weighted MR imaging and choline uptake in (11)C-choline PET/CT are correlated in pelvic lymph nodes in patients with prostate cancer.Molecular Imaging of Prostate Cancer Phospholipase D1 and choline kinase-α are interactive targets in breast cancer.Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.Mycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cells Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopy.Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer 1H/31P polarization transfer at 9.4 Tesla for improved specificity of detecting phosphomonoesters and phosphodiesters in breast tumor models.Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway.Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy Direct inhibition of choline kinase by a near-infrared fluorescent carbocyanine Choline kinase alpha and hexokinase-2 protein expression in hepatocellular carcinoma: association with survival.HR-MAS MR spectroscopy of breast cancer tissue obtained with core needle biopsy: correlation with prognostic factors.Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis.Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts.Clinical characteristics and biomarkers of breast cancer associated with choline concentration measured by 1H MRS.Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells Mechanisms of indomethacin-induced alterations in the choline phospholipid metabolism of breast cancer cells.Molecular and functional imaging of invasion and metastasis: windows into the metastatic cascade.A novel small molecule antagonist of choline kinase-α that simultaneously suppresses MAPK and PI3K/AKT signaling Choline metabolism in malignant transformation.

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P2860

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

http://www.wikidata.org/entity/Q34135239

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2002年の論文

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name

Increased choline kinase activ ...... tial novel antitumor strategy.

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Increased choline kinase activ ...... tial novel antitumor strategy.

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Increased choline kinase activ ...... tial novel antitumor strategy.

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Increased choline kinase activ ...... tial novel antitumor strategy.

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Increased choline kinase activ ...... tial novel antitumor strategy.

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Increased choline kinase activ ...... tial novel antitumor strategy.

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Increased choline kinase activ ...... tial novel antitumor strategy.

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Ana Ramírez de Molina

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Félix Bonilla

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Javier Silva

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José Javier Sánchez

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José María Silva

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Juan Carlos Lacal

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Maria Angeles Ramos

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Ruth Gutiérrez

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P2860

Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K

Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial

Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

Future prospects for the prevention and cure of breast cancer.

Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers.

Statistical approaches to the analysis of receiver operating characteristic (ROC) curves.

Choline kinase inhibitors as a novel approach for antiproliferative drug design.

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10.1038/SJ.ONC.1205556

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1013092478

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12082619

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