about
Shelterin complex and associated factors at human telomeresTelomere- and Telomerase-Associated Proteins and Their Functions in the Plant CellStructure and function of the telomeric CST complexAnalyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70Rvb2/reptin physically associates with telomerase in budding yeast.RPA facilitates telomerase activity at chromosome ends in budding and fission yeastsLength-dependent processing of telomeres in the absence of telomerase.Telomere DNA recognition in Saccharomycotina yeast: potential lessons for the co-evolution of ssDNA and dsDNA-binding proteins and their target sitesThe telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structuresCTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustionResponses to telomere erosion in plants.Telomere protection by TPP1/POT1 requires tethering to TIN2Duplication and functional specialization of the telomere-capping protein Cdc13 in Candida speciesMERISTEM DISORGANIZATION1 encodes TEN1, an essential telomere protein that modulates telomerase processivity in Arabidopsis.Rif1 supports the function of the CST complex in yeast telomere capping.Telomere Biology-Insights into an Intriguing Phenomenon.The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeresXenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract.Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus.Human CST promotes telomere duplex replication and general replication restart after fork stalling.SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.Rif2 promotes a telomere fold-back structure through Rpd3L recruitment in budding yeastHuman CST has independent functions during telomere duplex replication and C-strand fill-inTelomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner.Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase.Combinatorial recognition of a complex telomere repeat sequence by the Candida parapsilosis Cdc13AB heterodimerTpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association.A role for heterochromatin protein 1γ at human telomeres.The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats.The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch.Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulationQTL Mapping and Candidate Gene Analysis of Telomere Length Control Factors in Maize (Zea mays L.).SUMOylation regulates telomere length homeostasis by targeting Cdc13.ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in ArabidopsisMultiple pathways suppress telomere addition to DNA breaks in the Drosophila germline.STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function.Chromosome end protection by blunt-ended telomeresHuman CST abundance determines recovery from diverse forms of DNA damage and replication stress.Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
CST meets shelterin to keep telomeres in check.
@ast
CST meets shelterin to keep telomeres in check.
@en
CST meets shelterin to keep telomeres in check.
@nl
type
label
CST meets shelterin to keep telomeres in check.
@ast
CST meets shelterin to keep telomeres in check.
@en
CST meets shelterin to keep telomeres in check.
@nl
prefLabel
CST meets shelterin to keep telomeres in check.
@ast
CST meets shelterin to keep telomeres in check.
@en
CST meets shelterin to keep telomeres in check.
@nl
P2093
P1433
P1476
CST meets shelterin to keep telomeres in check.
@en
P2093
Eric Gilson
M Teresa Teixeira
Vincent Géli
P304
P356
10.1016/J.MOLCEL.2010.08.024
P577
2010-09-01T00:00:00Z