Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. - Wikidata - wikimedia - TriplyDB

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

http://www.wikidata.org/entity/Q34138234

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Impact of New Genomic Technologies on Understanding Adverse Drug Reactions New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity Pharmacogenetics and Predictive Testing of Drug Hypersensitivity Reactions Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity Progress in understanding the genomic basis for adverse drug reactions: a comprehensive review and focus on the role of ethnicity Human leucocyte antigen-adverse drug reaction associations: from a perspective of ethnicity.Pharmacogenomics of off-target adverse drug reactions.Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia.Pharmacogenetics of clozapine treatment response and side-effects in schizophrenia: an update.Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis.Personalized prescribing: a new medical model for clinical implementation of psychotropic drugs.Psychiatric Pharmacogenomics: How Close Are We?Worldwide Differences in Regulations of Clozapine Use.Hepatic Safety of Atypical Antipsychotics: Current Evidence and Future Directions.Clozapine's critical role in treatment resistant schizophrenia: ensuring both safety and use.Genome-wide association study of lymphoblast cell viability after clozapine exposure.The road to precision psychiatry: translating genetics into disease mechanisms.Incidence and risk estimate of drug-induced agranulocytosis in Hong Kong Chinese. A population-based case-control study.More than 25 years of genetic studies of clozapine-induced agranulocytosis.Clozapine as a Model for Antipsychotic Development.Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.[Dipyrone (metamizole) : Considerations on monitoring for early detection of agranulocytosis].Adverse drug reactions triggered by the common HLA-B*57:01 variant: a molecular docking study.Late Onset Agranulocytosis with Clozapine Associated with HLA DR4 Responding to Treatment with Granulocyte Colony-stimulating Factor: A Case Report and Review of Literature.Evaluating the Effect of the Changes in FDA Guidelines for Clozapine Monitoring.Psychiatric Genomics: An Update and an Agenda.HLAs: Key regulators of T-cell-mediated drug hypersensitivity.Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study.Adverse drug reactions triggered by the common HLA-B*57:01 variant: virtual screening of DrugBank using 3D molecular docking.Biomarkers of adverse drug reactions.Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population.Cost-effectiveness of HLA-DQB1/HLA-B pharmacogenetic-guided treatment and blood monitoring in US patients taking clozapine.Patient ethnicity and the risk of immune-mediated adverse drug reactions.Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs in HMMR as Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients.Clozapine Pharmacogenetic Studies in Schizophrenia: Efficacy and Agranulocytosis Critical assessment of approaches for molecular docking to elucidate associations of HLA alleles with adverse drug reactions How close are we to a pharmacogenomic test for clozapine-induced agranulocytosis?

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Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

http://www.wikidata.org/entity/Q34138234

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@ast

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@en

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@nl

type

label

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@ast

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@en

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@nl

prefLabel

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@ast

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@en

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

@nl

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Nature Communications

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Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

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Ana Alfirevic

http://www.w3.org/2001/XMLSchema#string

Anil K Malhotra

http://www.w3.org/2001/XMLSchema#string

Arthur L Holden

http://www.w3.org/2001/XMLSchema#string

Benjamin M Neale

http://www.w3.org/2001/XMLSchema#string

Chris Hilliard

http://www.w3.org/2001/XMLSchema#string

Deanna L Kelly

http://www.w3.org/2001/XMLSchema#string

Deborah L Levy

http://www.w3.org/2001/XMLSchema#string

Edwin J C G van den Oord

http://www.w3.org/2001/XMLSchema#string

Ephraim Gazit

http://www.w3.org/2001/XMLSchema#string

James L Kennedy

http://www.w3.org/2001/XMLSchema#string

P2860

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

A map of human genome variation from population-scale sequencing

A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals

Fast and accurate short read alignment with Burrows-Wheeler transform

PLINK: a tool set for whole-genome association and population-based linkage analyses

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

A method and server for predicting damaging missense mutations

Haploview: analysis and visualization of LD and haplotype maps

The Sequence Alignment/Map format and SAMtools

Principal components analysis corrects for stratification in genome-wide association studies

P2888

P304

4757

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10.1038/NCOMMS5757

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P407

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Munir Pirmohamed

Mark Joseph Daly

Alexander Tropsha

Jacqueline I Goldstein

Ingolf Cascorbi

Jeffrey Lieberman

P577

2014-09-04T00:00:00Z

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265611619

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1029858229

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25187353

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4155508

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