Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
about
Squalene-hopene cyclasesEnantioselective thiourea-catalyzed cationic polycyclizationsAttractive noncovalent interactions in asymmetric catalysis: links between enzymes and small molecule catalystsA case study in biomimetic total synthesis: polyolefin carbocyclizations to terpenes and steroidsComposite bacterial hopanoids and their microbial producers across oxygen gradients in the water column of the California CurrentIdentification and characterization of Rhodopseudomonas palustris TIE-1 hopanoid biosynthesis mutantsBiosynthesis of cholesterol and other sterolsSqualene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade anNovel hopanoid cyclases from the environment.Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse beta-carotene 15, 15'-monooxygenase.Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin.Transition-state charge stabilization through multiple non-covalent interactions in the guanidinium-catalyzed enantioselective Claisen rearrangementElectrophilic and nucleophilic enzymatic cascade reactions in biosynthesis.Mutagenesis approaches to deduce structure-function relationships in terpene synthases.Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach.Terpenoid synthase structures: a so far incomplete view of complex catalysis.Computational Studies on the Pt(II)-Catalyzed Cycloisomerization of 1,6-dienes into Bicyclopropanes: A Mechanistic Quandary Evaluated by DFT.Unusually cyclized triterpenes: occurrence, biosynthesis and chemical synthesis.Synthesis of arborane triterpenols by a bacterial oxidosqualene cyclase.Oxidative Cyclization in Natural Product Biosynthesisβ-Amyrin biosynthesis: catalytic mechanism and substrate recognition.Distribution of microbial terpenoid lipid cyclases in the global ocean metagenome.Distribution and Abundance of Hopanoid Producers in Low-Oxygen Environments of the Eastern Pacific Ocean.Activation-independent cyclization of monoterpenoids.Structural and Chemical Biology of Terpenoid Cyclases.Catalytic platinum-initiated cation-olefin reactions with alkene terminating groups.Functional analyses of Tyr420 and Leu607 of Alicyclobacillus acidocaldarius squalene-hopene cyclase. Neoachillapentaene, a novel triterpene with the 1,5,6-trimethylcyclohexene moiety produced through folding of the constrained boat structure.Synthesis of heterocyclic terpenoids by promiscuous squalene-hopene cyclases.Prokaryotic squalene-hopene cyclases can be converted to citronellal cyclases by single amino acid exchange.Squalene-hopene cyclase: insight into the role of the methyl group on the squalene backbone upon the polycyclization cascade. Enzymatic cyclization products of squalene analogs lacking a 26-methyl group and possessing a methyl group at C7 or C11.Enzymatic cyclization reactions of geraniol, farnesol and geranylgeraniol, and those of truncated squalene analogs having C20 and C25 by recombinant squalene cyclase.Migrated Hopene Synthases from Colysis pothifolia and Identification of a Migration Switch Controlling the Number of 1,2-Hydride and Methyl Shifts.Squalene cyclase and oxidosqualene cyclase from a fern.Entropy is key to the formation of pentacyclic terpenoids by enzyme-catalyzed polycyclization.Euphorbia tirucalli β-Amyrin Synthase: Critical Roles of Steric Sizes at Val483 and Met729 and the CH-π Interaction between Val483 and Trp534 for Catalytic Action.The triterpene cyclase protein family: a systematic analysis.Analysis of the Catalytic Mechanism of Bifunctional Triterpene/Sesquarterpene Cyclase: Tyr167 Functions To Terminate Cyclization of Squalene at the Bicyclic Step
P2860
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P2860
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@ast
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@en
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@nl
type
label
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@ast
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@en
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@nl
prefLabel
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@ast
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@en
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@nl
P356
P1476
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
@en
P2093
Tsutomu Hoshino
Tsutomu Sato
P304
P356
10.1039/B108995C
P407
P577
2002-02-01T00:00:00Z