Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
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Reduction of plasma triglycerides in apolipoprotein C-II transgenic mice overexpressing lipoprotein lipase in muscleApolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activatorsRegulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and betaDifferential effects of activation of liver X receptor on plasma lipid homeostasis in wild-type and lipoprotein clearance-deficient miceCytochrome P450 1A1 promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice.Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and ESTAT1 interacts with RXRα to upregulate ApoCII gene expression in macrophages.A novel apolipoprotein C-II mimetic peptide that activates lipoprotein lipase and decreases serum triglycerides in apolipoprotein E-knockout miceLipoprotein lipase: from gene to obesity.Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL.A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice.Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia.A novel APOC2 gene mutation identified in a Chinese patient with severe hypertriglyceridemia and recurrent pancreatitisCreation of Apolipoprotein C-II (ApoC-II) Mutant Mice and Correction of Their Hypertriglyceridemia with an ApoC-II Mimetic Peptide.Age, APOE and sex: Triad of risk of Alzheimer's disease.Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein ClIn the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein ELiver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr-/- mice.The relationship between high density lipoprotein subclass profile and apolipoprotein concentrations.Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice.Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes.A short proximal promoter and the distal hepatic control region-1 (HCR-1) contribute to the liver specificity of the human apolipoprotein C-II gene. Hepatic enhancement by HCR-1 requires two proximal hormone response elements which have different biApolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins.COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity.
P2860
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P2860
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@ast
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@en
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@nl
type
label
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@ast
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@en
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@nl
prefLabel
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@ast
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@en
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@nl
P2093
P2860
P356
P1476
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
@en
P2093
D W Rosenberg
H N Ginsberg
I J Goldberg
J L Breslow
N S Shachter
R Ramakrishnan
P2860
P304
P356
10.1172/JCI117151
P407
P577
1994-04-01T00:00:00Z