Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome. - Wikidata - wikimedia - TriplyDB

Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.

Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.

http://www.wikidata.org/entity/Q34143892

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Human Immunodeficiencies Related to Defective APC/T Cell Interaction Actin nucleators in the nucleus: an emerging theme Actin cytoskeletal defects in immunodeficiency Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network Disruption of hSWI/SNF complexes in T cells by WAS mutations distinguishes X-linked thrombocytopenia from Wiskott-Aldrich syndrome Current and emerging treatment options for Wiskott-Aldrich syndrome.T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo.Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes Nuclear actin and transcriptional activation.Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression.Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells.The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.Autoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells Genetics of allergy and allergic sensitization: common variants, rare mutations Cellular functions of WASP family proteins at a glance.Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.Wiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development.Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection Nuclear Actin in Development and Transcriptional Reprogramming Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins.Wiskott-Aldrich syndrome protein--dynamic regulation of actin homeostasis: from activation through function and signal termination in T lymphocytes.Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression.Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott-Aldrich Syndrome.Insights into primary immune deficiency from quantitative microscopy.N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination.Nuclear actin in transcriptional reprogramming by oocytes: are actin nucleators key players?B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome.Nuclear Wiskott-Aldrich syndrome protein co-regulates T cell factor 1-mediated transcription in T cells.Clinical Manifestations and Pathophysiological Mechanisms of the Wiskott-Aldrich Syndrome.Alternative control: what's WASp doing in the nucleus?The Arp2/3 Regulatory System and Its Deregulation in Cancer.Wiskott-Aldrich syndrome protein: Emerging mechanisms in immunity.Molecular Control of Actin Dynamics In Vivo: Insights from Drosophila.Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.Nuclear F-actin enhances the transcriptional activity of β-catenin by increasing its nuclear localization and binding to chromatin.TCR Signaling Abnormalities in Human Th2-Associated Atopic Disease.Nuclear ARP2/3 drives DNA break clustering for homology-directed repair

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Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.

http://www.wikidata.org/entity/Q34143892

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年论文

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name

Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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type

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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SCITRANSLMED.3000813

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Science Translational Medicine

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Nuclear role of WASp in the pa ...... uman Wiskott-Aldrich syndrome.

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Annamalai Selvakumar

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Archana Ramgopal

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Fabio Candotti

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Koustav Sarkar

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Matthew D Taylor

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Ponnappa Kottangada

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Sanjoy Sadhukhan

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Sheryl D'Silva

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Yatin M Vyas

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P2860

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.

A novel transcription factor, T-bet, directs Th1 lineage commitment

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks

Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression

Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assembly

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

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37ra44

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37

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44698385

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20574068

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positive regulation of transcription from RNA polymerase II promoter

WASP actin nucleation promoting factor

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2943146

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