Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8
about
GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasingIntegrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation.Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system.Matters of context guide future research in TGFβ superfamily signaling.Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins.Hepatic Stellate Cells Inhibit T Cells through Active TGF-β1 from a Cell Surface-Bound Latent TGF-β1/GARP Complex.Garp as a therapeutic target for modulation of T regulatory cell function.Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance.Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA.Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.Exploring the Role of RGD-Recognizing Integrins in Cancer.Regulatory T cells in Acute and Chronic Kidney Diseases.D-mannose induces regulatory T cells and suppresses immunopathology.Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8.Mesenchymal stem cells inhibit T cell activation by releasing TGF-β1 from TGF-β1/GARP complex.Serum and Extracellular Vesicle MicroRNAs miR-423, miR-199, and miR-93* As Biomarkers for Acute Graft-versus-Host Disease.Role of GARP in the activation of latent TGF-β1.Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer.Foxp3-independent mechanism by which TGF-β controls peripheral T cell tolerance.A Context-Dependent Role for αv Integrins in Regulatory T Cell Accumulation at Sites of Inflammation.TGF-β in T Cell Biology: Implications for Cancer Immunotherapy.
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P2860
Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Release of active TGF-β1 from ...... lls is mediated by integrin β8
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Release of active TGF-β1 from ...... lls is mediated by integrin β8
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Release of active TGF-β1 from ...... lls is mediated by integrin β8
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label
Release of active TGF-β1 from ...... lls is mediated by integrin β8
@ast
Release of active TGF-β1 from ...... lls is mediated by integrin β8
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Release of active TGF-β1 from ...... lls is mediated by integrin β8
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prefLabel
Release of active TGF-β1 from ...... lls is mediated by integrin β8
@ast
Release of active TGF-β1 from ...... lls is mediated by integrin β8
@en
Release of active TGF-β1 from ...... lls is mediated by integrin β8
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P2860
P356
P1476
Release of active TGF-β1 from ...... lls is mediated by integrin β8
@en
P2093
Angela M Thornton
Ethan M Shevach
P2860
P304
P356
10.4049/JIMMUNOL.1401102
P407
P577
2014-08-15T00:00:00Z