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Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

http://www.wikidata.org/entity/Q34147023

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Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response The Role of Cyclo(His-Pro) in Neurodegeneration Traumatic brain injury: pathophysiology for neurocritical care Efficacy of progesterone for moderate to severe traumatic brain injury: a meta-analysis of randomized clinical trials Systems biology approaches for discovering biomarkers for traumatic brain injury Neuroprotection for traumatic brain injury Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date Neuroprotective strategies for traumatic brain injury: improving clinical translation Animal models of traumatic brain injury Using Drosophila as an integrated model to study mild repetitive traumatic brain injury.Utilizing pharmacotherapy and mesenchymal stem cell therapy to reduce inflammation following traumatic brain injury Emerging therapies in traumatic brain injury Hsp70 inducer, 17-allylamino-demethoxygeldanamycin, provides neuroprotection via anti-inflammatory effects in a rat model of traumatic brain injury Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury Subacute intranasal administration of tissue plasminogen activator promotes neuroplasticity and improves functional recovery following traumatic brain injury in rats Structured evaluation of rodent behavioral tests used in drug discovery research.CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury.Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury.Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice.Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury Neuroimaging after mild traumatic brain injury: review and meta-analysis.Angiotensin receptor type 2 activation induces neuroprotection and neurogenesis after traumatic brain injury.Comparison of neurite density measured by MRI and histology after TBI.Postsynaptic scaffold protein Homer 1a protects against traumatic brain injury via regulating group I metabotropic glutamate receptors.Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?Therapeutic Prospective of Infused Allogenic Cultured Mesenchymal Stem Cells in Traumatic Brain Injury Mice: A Longitudinal Proton Magnetic Resonance Spectroscopy Assessment A new avenue for lithium: intervention in traumatic brain injury.The Effects of Chunghyul-Dan, an Agent of Korean Medicine, on a Mouse Model of Traumatic Brain Injury The Role of Substance P in Secondary Pathophysiology after Traumatic Brain Injury.Microglial Activation in Traumatic Brain Injury.bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma Low-level laser therapy effectively prevents secondary brain injury induced by immediate early responsive gene X-1 deficiency.Therapeutic effects of pharmacologically induced hypothermia against traumatic brain injury in mice.Is progesterone a worthy candidate as a novel therapy for traumatic brain injury?Development of a database for translational spinal cord injury research Transcranial low-level laser therapy enhances learning, memory, and neuroprogenitor cells after traumatic brain injury in mice.Expression of miRNAs and their cooperative regulation of the pathophysiology in traumatic brain injury Selective CDK inhibitors: promising candidates for future clinical traumatic brain injury trials.

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Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

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Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial

Clinical trials in head injury

Drugs acting on SUR1 to treat CNS ischemia and trauma

Classification of traumatic brain injury for targeted therapies

Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study

NXY-059 for acute ischemic stroke

Progesterone differentially regulates pro- and anti-apoptotic gene expression in cerebral cortex following traumatic brain injury in rats

Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage

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traumatic brain injury

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