A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning.
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Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebratesDorsal-ventral gene expression in the Drosophila embryo reflects the dynamics and precision of the dorsal nuclear gradient.Specified neural progenitors sort to form sharp domains after noisy Shh signaling.Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversityPtch1 and Gli regulate Shh signalling dynamics via multiple mechanisms.Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressorsGlycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage.The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cordNeural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional ProgramsSoxB1-driven transcriptional network underlies neural-specific interpretation of morphogen signalsShh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.Pattern, growth, and control.Spatiotemporal mechanisms of morphogen gradient interpretationMolecular genetic control of cell patterning and fate determination in the developing ventral spinal cord.EMBRYO DEVELOPMENT. BMP gradients: A paradigm for morphogen-mediated developmental patterning.The effects of the toxic cyanobacterium Limnothrix (strain AC0243) on Bufo marinus larvae.Directed Differentiation of V3 Interneurons from Mouse Embryonic Stem Cells.Gene length may contribute to graded transcriptional responses in the Drosophila embryo.Arx together with FoxA2, regulates Shh floor plate expression.Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer.Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.Cadherin-7 enhances Sonic Hedgehog signalling by preventing Gli3 repressor formation during neural tube patterning.Zebrafish Rfx4 controls dorsal and ventral midline formation in the neural tube.Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord.FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord.Alterations in Morphology and Adult Neurogenesis in the Dentate Gyrus of Patched1 Heterozygous Mice.Moving the Shh Source over Time: What Impact on Neural Cell Diversification in the Developing Spinal Cord?
P2860
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P2860
A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning.
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2010 nî lūn-bûn
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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
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2010年论文
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A homeodomain feedback circuit ...... ing ventral neural patterning.
@ast
A homeodomain feedback circuit ...... ing ventral neural patterning.
@en
A homeodomain feedback circuit ...... ing ventral neural patterning.
@nl
type
label
A homeodomain feedback circuit ...... ing ventral neural patterning.
@ast
A homeodomain feedback circuit ...... ing ventral neural patterning.
@en
A homeodomain feedback circuit ...... ing ventral neural patterning.
@nl
prefLabel
A homeodomain feedback circuit ...... ing ventral neural patterning.
@ast
A homeodomain feedback circuit ...... ing ventral neural patterning.
@en
A homeodomain feedback circuit ...... ing ventral neural patterning.
@nl
P2093
P50
P356
P1433
P1476
A homeodomain feedback circuit ...... ing ventral neural patterning.
@en
P2093
Christopher W Uhde
Hans-Henning Arnold
John L Rubenstein
José M Dias
Lori Sussel
Madelen Lek
Sanja Kurdija
Thomas M Jessell
P304
P356
10.1242/DEV.054288
P407
P577
2010-12-01T00:00:00Z