about
Physiology and pharmacology of the vanilloid receptorTRPV1: A Potential Drug Target for Treating Various Diseases.TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells.Chemical nociception in the jejunum induced by capsaicin.Gastrointestinal pain in functional bowel disorders: sensory neurons as novel drug targets.TRPV1 activation is not an all-or-none event: TRPV1 partial agonism/antagonism and its regulatory modulation.Conformationally constrained analogues of N'-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonists.Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells.TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cellsStructure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1)The SAR analysis of TRPV1 agonists with the α-methylated B-regionDifferential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats.Screening TRPV1 antagonists for the treatment of pain: lessons learned over a decade.Recent Advances in Stereoselective Drug Targeting.Novel methodology to identify TRPV1 antagonists independent of capsaicin activation.The chimeric approach reveals that differences in the TRPV1 pore domain determine species-specific sensitivity to block of heat activation.Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists.Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1.Hypersensitivity for capsaicin in patients with functional dyspepsia.Design, synthesis and biological evaluation of B-region modified diarylalkyl amide analogues as novel TRPV1 antagonists.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
High affinity antagonists of the vanilloid receptor.
@ast
High affinity antagonists of the vanilloid receptor.
@en
High affinity antagonists of the vanilloid receptor.
@nl
type
label
High affinity antagonists of the vanilloid receptor.
@ast
High affinity antagonists of the vanilloid receptor.
@en
High affinity antagonists of the vanilloid receptor.
@nl
prefLabel
High affinity antagonists of the vanilloid receptor.
@ast
High affinity antagonists of the vanilloid receptor.
@en
High affinity antagonists of the vanilloid receptor.
@nl
P2093
P356
P1476
High affinity antagonists of the vanilloid receptor.
@en
P2093
Attila Toth
Jacqueline D Welter
Jeewoo Lee
Jiyoun Lee
Peter M Blumberg
Richard Tran
Sang Uk Kang
Tamas Szabo
Young-Ger Suh
P304
P356
10.1124/MOL.62.4.947
P577
2002-10-01T00:00:00Z