The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
about
Autophagy signal transduction by ATG proteins: from hierarchies to networksRole of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagyAnesthesia-induced developmental neurodegeneration: the role of neuronal organelles.Endoplasmic reticulum (ER) stress in cumulus-oocyte complexes impairs pentraxin-3 secretion, mitochondrial membrane potential (DeltaPsi m), and embryo development.Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics.Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death.General anesthetic isoflurane modulates inositol 1,4,5-trisphosphate receptor calcium channel opening.Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergeticsThe BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release.The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondriaThe type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca²⁺-release channel.Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagyExpression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis.PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stressHERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptorUnique Regulatory Properties of Heterotetrameric Inositol 1,4,5-Trisphosphate Receptors Revealed by Studying Concatenated Receptor Constructs.Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai120-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.The role of autophagy in cardiac hypertrophy.Characterization of the effect of the mitochondrial protein Hint2 on intracellular Ca(2+) dynamicsDual effects of neuroprotection and neurotoxicity by general anesthetics: role of intracellular calcium homeostasis.Regulation of the autophagic bcl-2/beclin 1 interaction.Blockade of RyRs in the ER Attenuates 6-OHDA-Induced Calcium Overload, Cellular Hypo-Excitability and Apoptosis in Dopaminergic NeuronsWhat model organisms and interactomics can reveal about the genetics of human obesity.Mitochondrial Ca²⁺ homeostasis: mechanism, role, and tissue specificities.The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.Polycystins and cellular Ca2+ signaling.Ca²⁺-sensor proteins in the autophagic and endocytic traffic.A matter of life, death and diseases: mitochondria from a proteomic perspective.Regulation of connexin- and pannexin-based channels by post-translational modifications.Perturbed mitochondrial Ca2+ signals as causes or consequences of mitophagy induction.Bcl-2 proteins and calcium signaling: complexity beneath the surface.Functional role of TRP channels in modulating ER stress and Autophagy.CISD2 expression is a novel marker correlating with pelvic lymph node metastasis and prognosis in patients with early-stage cervical cancer.Regulation of autophagy by Ca2.Calcium alterations signal either to senescence or to autophagy induction in stem cells upon oxidative stress.Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation
P2860
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P2860
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The IP
@nl
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@ast
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@en
type
label
The IP
@nl
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@ast
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@en
prefLabel
The IP
@nl
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@ast
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@en
P2093
P1476
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
@en
P2093
Geert Bultynck
Giovanni Monaco
Humbert De Smedt
Jan B Parys
Jean-Paul Decuypere
Ludwig Missiaen
P304
P356
10.1016/J.BBAMCR.2010.11.023
P407
P577
2010-12-10T00:00:00Z