Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells - Wikidata - wikimedia - TriplyDB

Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells

Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells

http://www.wikidata.org/entity/Q34154767

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Genome-wide profiles of methylation, microRNAs, and gene expression in chemoresistant breast cancer Phospholipase Cδ1 suppresses cell migration and invasion of breast cancer cells by modulating KIF3A-mediated ERK1/2/β- catenin/MMP7 signalling.Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF-κB signaling Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer.Non-invasive prediction of preterm birth in women with cervical insufficiency or an asymptomatic short cervix (≤25 mm) by measurement of biomarkers in the cervicovaginal fluid.Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer.Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer.Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells DKK3 blocked translocation of β-catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc-3 cell.Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy.Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells.Protocadherin 17 functions as a tumor suppressor suppressing Wnt/β-catenin signaling and cell metastasis and is frequently methylated in breast cancer.Epigenetic inactivation of mir-34b/c in addition to mir-34a and DAPK1 in chronic lymphocytic leukemia.DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.Prostate apoptosis response 4 (PAR4) expression modulates WNT signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity.Regulation of breast cancer stem cell features.The Dkk3 gene encodes a vital intracellular regulator of cell proliferation.Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes.Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease.Dickkopf-3 Ablation Attenuates the Development of Atherosclerosis in ApoE-Deficient Mice.Dickkopf-3 Contributes to the Regulation of Anti-Tumor Immune Responses by Mesenchymal Stem Cells.Expression analysis of Dickkopf-related protein 3 (Dkk3) suggests its pleiotropic roles for a secretory glycoprotein in adult mouse.High-frequency deregulated expression of Wnt signaling pathway members in breast carcinomas.MYCN is a novel oncogenic target in adult B-ALL that activates the Wnt/β-catenin pathway by suppressing DKK3.Down-regulation of Frizzled-7 expression inhibits migration, invasion, and epithelial-mesenchymal transition of cervical cancer cell lines.Breast Cancer Heterogeneity: A focus on Epigenetics and In Vitro 3D Model Systems Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis Prognostic value of DKK2 from the Dickkopf family in human breast cancer Paired box 5 is a novel marker of breast cancers that is frequently downregulated by methylation

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P2860

Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells

http://www.wikidata.org/entity/Q34154767

description

2013 nî lūn-bûn

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2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2013 թվականի հուլիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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type

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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Journal of Cellular and Molecular Medicine

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Epigenetic silencing of the WN ...... ulation in breast cancer cells

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P2093

Guosheng Ren

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Lan Zhong

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Lili Li

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Qian Tao

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Tingxiu Xiang

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Weiyan Peng

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Xuedong Yin

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Zhu Qiu

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P2860

Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

Functional and structural diversity of the human Dickkopf gene family

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling

Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells

Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma

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1236-1246

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scholarly article

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10.1111/JCMM.12099

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10

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17

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23890219

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4159020

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