Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7.
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Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data.pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57Bl6 and ApoE Knockout Mice Fed a Western Diet.Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation.Engineering CHO cell growth by stable manipulation of miRNA expression.Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferationMiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.MiRNA mimic screen for improved expression of functional neurotensin receptor from HEK293 cellsProfiling conserved microRNA expression in recombinant CHO cell lines using Illumina sequencing.Stable inhibition of mmu-miR-466h-5p improves apoptosis resistance and protein production in CHO cells.Advances in Mammalian cell line development technologies for recombinant protein production.CHO microRNA engineering is growing up: recent successes and future challenges.CHO cells in biotechnology for production of recombinant proteins: current state and further potential.An 'omics approach towards CHO cell engineering.Towards next generation CHO cell biology: Bioinformatics methods for RNA-Seq-based expression profiling.miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.Hyperosmotic stimulus study discloses benefits in ATP supply and reveals miRNA/mRNA targets to improve recombinant protein production of CHO cells.Stable overexpression of miR-17 enhances recombinant protein production of CHO cells.miR-143 targets MAPK7 in CHO cells and induces a hyperproductive phenotype to enhance production of difficult-to-express proteins.A functional high-content miRNA screen identifies miR-30 family to boost recombinant protein production in CHO cells.Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells.CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells.Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cellsRegulation of miR-29b-1/a transcription and identification of target mRNAs in CHO-K1 cells.Functional heterogeneity and heritability in CHO cell populations.Conserved microRNA function as a basis for Chinese hamster ovary cell engineering.Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells.CHO-Omics Review: The Impact of Current and Emerging Technologies on Chinese Hamster Ovary Based Bioproduction.Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype.miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality.Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures.Cell Line Techniques and Gene Editing Tools for Antibody Production: A Review.
P2860
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P2860
Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@ast
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@en
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@nl
type
label
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@ast
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@en
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@nl
prefLabel
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@ast
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@en
Engineering CHO cell growth an ...... ty by overexpression of miR-7.
@nl
P2093
P1476
Engineering CHO cell growth an ...... ity by overexpression of miR-7
@en
P2093
P304
P356
10.1016/J.JBIOTEC.2010.12.005
P577
2010-12-15T00:00:00Z