Total Synthesis of Nominal Diazonamides-Part 2: On the True Structure and Origin of Natural Isolates Funding provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support), the Robert A. Wel
about
Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity.Structure validation in chemical crystallography.A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products.Methodology for the Synthesis of Substituted 1,3-Oxazoles.Efficient Suzuki and Stille Reactions for Regioselective Strategies of Incorporation of the 1,3-Oxazole Heterocycle. Mild Desulfonylation for the Synthesis of C-4 and C-5 Monosubstituted Oxazoles.Total Synthesis of Nominal Diazonamides-Part 1: Convergent Preparation of the Structure Proposed for (-)-Diazonamide A Funding provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support),Natural products: a continuing source of novel drug leadsInteractions of antimitotic peptides and depsipeptides with tubulin.The palladium catalyzed asymmetric addition of oxindoles and allenes: an atom-economical versatile method for the construction of chiral indole alkaloidsDiazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division.The essence of total synthesisUtilizing the power of microbial genetics to bridge the gap between the promise and the application of marine natural products.Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.A concise formal synthesis of diazonamide A by the stereoselective construction of the C10 quaternary centerGeneral methodology for the preparation of 2,5-disubstituted-1,3-oxazolesEnantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbonStructural characterization of an enantiomerically pure amino acid imidazolide and direct formation of the beta-lactam nucleus from an alpha-amino acid.Total synthesis of atrochamins F, H, I, and J through cascade reactions.Diazonamide support studies: stereoselective formation of the C10 chiral center in both the CDEFG and AEFG fragmentsAzonazine, a novel dipeptide from a Hawaiian marine sediment-derived fungus, Aspergillus insulicola.Nitrogen and hydrogen adsorption by an organic microporous crystalAn expedient formal total synthesis of (-)-diazonamide A via a powerful, stereoselective O-aryl to C-aryl migration to form the C10 quaternary center.Dereplication and de novo sequencing of nonribosomal peptides.External oxidant-free electrooxidative [3 + 2] annulation between phenol and indole derivatives.Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography.The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.Electrolytic macrocyclizations: scalable synthesis of a diazonamide-based drug development candidate.Palladium(II)-catalyzed dehydrogenative cross-coupling between two C(sp3)-H bonds: unexpected C=C bond formation.Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells.One-step formation of dihydrofuranoindoline cores promoted by a hypervalent iodine reagent.Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.Pardon the Interruption: A Modification of Fischer's Venerable Reaction for the Synthesis of Heterocycles and Natural Products.DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapyGold-catalysed synthesis of amino acid-derived 2,5-disubstituted oxazoles
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P2860
Total Synthesis of Nominal Diazonamides-Part 2: On the True Structure and Origin of Natural Isolates Funding provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support), the Robert A. Wel
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
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2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
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name
Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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P2093
P1433
P1476
Total Synthesis of Nominal Dia ...... ty support), the Robert A. Wel
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P2093
Anthony W. G. Burgett
Carlos Amezcua
Lothar Esser
Patrick G. Harran
P2860
P304
P356
10.1002/1521-3773(20011217)40:24<4770::AID-ANIE4770>3.0.CO;2-T
P577
2001-12-01T00:00:00Z