Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death.
about
Cytoplasmic vacuolization in cell death and survivalSpatial regulation of epidermal growth factor receptor signaling by endocytosisMolecular targeted approaches to cancer therapy and prevention using chalconesMethuosis: nonapoptotic cell death associated with vacuolization of macropinosome and endosome compartments.Synthesis and biological evaluation of indolyl-pyridinyl-propenones having either methuosis or microtubule disruption activityMechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation.Novel indolyl-chalcones target stathmin to induce cancer cell death.Microwave-assisted synthesis of 3-nitroindoles from N-aryl enamines via intramolecular arene-alkene couplingPreparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and PyrrolesCD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling.Advances and challenges in the molecular biology and treatment of glioblastoma-is there any hope for the future?Non-apoptotic cell death associated with perturbations of macropinocytosis.Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase.Novel synthetic chalcones induce apoptosis in the A549 non-small cell lung cancer cells harboring a KRAS mutation.Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolyl-pyridinyl-propenones: Effects on potency and mode of activity.Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents.Chalcone: A Privileged Structure in Medicinal Chemistry.Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones.Assessments of iodoindoles and abamectin as inducers of methuosis in pinewood nematode, Bursaphelenchus xylophilusVacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells.Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.Palladium-catalysed direct C-2 methylation of indoles.Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency".Novel N-Substituted 2-(2-(Adamantan-1-yl)-1H-Indol-3-yl)-2-Oxoacetamide Derivatives: Synthesis and Biological Evaluation.
P2860
Q26743410-69E4726F-D322-43DC-9379-B27E4F7CF2EEQ26829168-47497B59-BE40-49D5-A8B2-F12C0474E1ECQ27021479-3717BFE1-3891-45F5-B244-2FB0813AD182Q27692058-FF91C379-362C-4ED7-8174-725E1D38377BQ35179218-6E1C571B-A43C-47CB-ACCF-BB867CCA3700Q35911995-D72DA303-9639-43F3-A34A-084326DA7CC7Q35961195-5376FF3D-96D5-401B-9734-8C93B3B86D5EQ36546246-0AB4AAFA-9B85-415A-8B46-78ED1C16A6C0Q37040566-111CB320-348B-4D61-96D0-EBF4BA2779A0Q37694869-E6D4183A-D44F-48B1-BFDB-B581AD4299A6Q38364234-250CB5E9-6959-4D1F-BEA3-D517D8AD657AQ38374734-3C130A2A-AB6A-4202-8B8C-2965D394C65CQ38701564-3C6BC640-7AD1-4FB9-A071-2F746B94F8E6Q38733237-E44F9731-3847-4DA3-BB6B-18DF5AF4D441Q38762262-D5006BDA-69E8-4313-9532-2F97A0D714D2Q38763764-09BFABFA-19D2-4D3C-A90F-31E1DB85857CQ39295083-A6972F37-A97C-4F74-A716-59B0AC208B48Q41938084-74512500-0FC4-414C-8B7B-ADED0238E2E4Q42339231-6E7C42F5-E862-4539-82A2-DF3ECAAE9D49Q47997097-4E77C7F7-AFD1-45DF-8A46-721812A8B7B7Q48940486-820BDF2B-3B0E-4CA0-9B35-60F4148C757CQ51245689-05DBD4AF-0D34-4CA2-8E09-06190B88F7A7Q52605133-1EDD2BBB-ED36-4B09-920C-1CE9132BFAD8Q52983274-A7DC8CBF-2421-4434-9C49-BA2AF40E8672Q53102840-3FD8EA6F-8D40-49E4-9B93-EDAC3BBFE460
P2860
Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@ast
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@en
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@nl
type
label
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@ast
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@en
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@nl
prefLabel
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@ast
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@en
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@nl
P2093
P2860
P356
P1476
Synthesis and evaluation of in ...... pe of nonapoptotic cell death.
@en
P2093
Ashley M Young
Jean H Overmeyer
Michael W Robinson
Paul W Erhardt
William A Maltese
P2860
P304
P356
10.1021/JM201006X
P407
P577
2012-02-28T00:00:00Z