Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.
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Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2′-deoxyadenosine and the cytotoxic drug, 2-fluoroadenineInsights into Phosphate Cooperativity and Influence of Substrate Modifications on Binding and Catalysis of Hexameric Purine Nucleoside PhosphorylasesAntitumor effects of a dual-specific lentiviral vector carrying the Escherichia coli purine nucleoside phosphorylase gene.A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndromeEnhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.Clofarabine in leukemia.The role of clofarabine in acute myeloid leukemia.Gene therapy and targeted toxins for glioma.Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancerDevelopment of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues.PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?Clofarabine in the treatment of myelodysplastic syndromes.Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.Regioselective metalation of 6-methylpurines: synthesis of fluoromethyl purines and related nucleosides for suicide gene therapy of cancer.Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.Clofarabine combinations as acute myeloid leukemia salvage therapy.Synthesis of fluorinated nucleosides.Convenient synthesis of 2'-deoxy-2-fluoroadenosine from 2-fluoroadenine.Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.Gene therapy and targeted toxins for glioma
P2860
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P2860
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@ast
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@en
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@nl
type
label
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@ast
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@en
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@nl
prefLabel
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@ast
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@en
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@nl
P2093
P2860
P356
P1433
P1476
Antitumor activity of 2-fluoro ...... rine nucleoside phosphorylase.
@en
P2093
Abdalla E A Hassan
Eric J Sorscher
John A Secrist
Paula W Allan
William B Parker
William R Waud
P2860
P2888
P356
10.1038/SJ.CGT.7700520
P577
2003-01-01T00:00:00Z