CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.
about
Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cellsMechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivoCaveolin-1: An Oxidative Stress-Related Target for Cancer Prevention.CAV1 promotes HCC cell progression and metastasis through Wnt/β-catenin pathway.Predictive biomarkers for dasatinib treatment in melanoma.Cell-specific dual role of caveolin-1 in pulmonary hypertension.A tumor-suppressing function in the epithelial adhesion protein Trask.A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells.Phase I clinical trial of the Src inhibitor dasatinib with dacarbazine in metastatic melanomaIncreased vascularity and spontaneous metastasis of breast cancer by hedgehog signaling mediated upregulation of cyr61.Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration.The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis.Characterization of breast cancer interstitial fluids by TmT labeling, LTQ-Orbitrap Velos mass spectrometry, and pathway analysis.Cav1 suppresses tumor growth and metastasis in a murine model of cutaneous SCC through modulation of MAPK/AP-1 activationPhosphotyrosine profiling of curcumin-induced signaling.Cross-talk between Dopachrome Tautomerase and Caveolin-1 Is Melanoma Cell Phenotype-specific and Potentially Involved in Tumor Progression.MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK).Connexins and the gap in context.Caveolin-1 as a promoter of tumour spreading: when, how, where and why.Caveolin-1-negative head and neck squamous cell carcinoma primary tumors display increased epithelial to mesenchymal transition and prometastatic properties.Lymph node-induced immune tolerance in chronic lymphocytic leukaemia: a role for caveolin-1.Tyrosine kinase inhibition reverses TDP-43 effects on synaptic protein expression, astrocytic function and amino acid dis-homeostasis.Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models.Polarised clathrin-mediated endocytosis of EGFR during chemotactic invasion.The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis.E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells.Caveolin 1 expression correlates with poor prognosis and focal adhesion kinase expression in gastric cancer.Cav1 inhibits benign skin tumor development in a two-stage carcinogenesis model by suppressing epidermal proliferation.Lycorine inhibits breast cancer growth and metastasis via inducing apoptosis and blocking Src/FAK-involved pathway.Lactoferrin inhibits melanogenesis by down-regulating MITF in melanoma cells and normal melanocytes.Absence of caveolin-1 alters heat shock protein expression in spontaneous mammary tumors driven by Her-2/neu expression.PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing.
P2860
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P2860
CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@ast
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@en
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@nl
type
label
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@ast
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@en
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@nl
prefLabel
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@ast
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@en
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@nl
P2093
P2860
P50
P1433
P1476
CAV1 inhibits metastatic poten ...... rin/Src/FAK signaling pathway.
@en
P2093
Andrew E Aplin
Casey Trimmer
Franco Capozza
Gloria Bonuccelli
Janet N Milliman
Kristin M Daumer
Richard G Pestell
P2860
P304
P356
10.1158/0008-5472.CAN-10-0900
P407
P577
2010-08-13T00:00:00Z