Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL).
about
Amyloid heart disease. New frontiers and insights in pathophysiology, diagnosis, and management.Amyloid formation in light chain amyloidosisAltered Dimer Interface Decreases Stability in an Amyloidogenic ProteinStructural Alterations within Native Amyloidogenic Immunoglobulin Light ChainsSalts enhance both protein stability and amyloid formation of an immunoglobulin light chainBiologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.Solid-state NMR chemical shift assignments for AL-09 VL immunoglobulin light chain fibrils.Utility of Doppler myocardial imaging, cardiac biomarkers, and clonal immunoglobulin genes to assess left ventricular performance and stratify risk following peripheral blood stem cell transplantation in patients with systemic light chain amyloidosiCardiac amyloidosis: pathogenesis, clinical context, diagnosis and management options.Germ line origin and somatic mutations determine the target tissues in systemic AL-amyloidosis.Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chainsMutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.Clinical features and treatment response of light chain (AL) amyloidosis diagnosed in patients with previous diagnosis of multiple myelomaClinical diagnosis and typing of systemic amyloidosis in subcutaneous fat aspirates by mass spectrometry-based proteomicsThe critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chainConsequences of receptor editing at the lambda locus: multireactivity and light chain secretion.A strategy for synthesis of pathogenic human immunoglobulin free light chains in E. coli.Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chainsDifferential effects on light chain amyloid formation depend on mutations and type of glycosaminoglycansAmyloid nephropathyFactors associated with an increased risk of vertebral fracture in monoclonal gammopathies of undetermined significance.Al amyloidosisThe genetics of the amyloidoses: interactions with immunity and inflammation.Perspectives in treatment of AL amyloidosis.Recruitment of Light Chains by Homologous and Heterologous Fibrils Shows Distinctive Kinetic and Conformational Specificity.Light chain amyloidosis - current findings and future prospects.ALkappa(I) (UNK) - primary structure of an AL-amyloid protein presenting an organ-limited subcutaneous nodular amyloid syndrome of long duration. Case report and review.The risk of renal disease is increased in lambda myeloma with bone marrow amyloid depositsA review on advanced atrioventricular block in young or middle-aged adults.Systemic amyloidoses.Pathophysiology and treatment of systemic amyloidosis.Improving strategies for the diagnosis of cardiac amyloidosis.Amyloidosis: an unusual cause of upper gastrointestinal bleeding.Addressing Common Questions Encountered in the Diagnosis and Management of Cardiac Amyloidosis.The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable DomainsThe Lung in Dysregulated States of Humoral Immunity.A case of fatal intrahepatic cholestasis with primary AL amyloidosis: is early diagnosis possible?The effects of sodium sulfate, glycosaminoglycans, and Congo red on the structure, stability, and amyloid formation of an immunoglobulin light-chain protein.Aggregates, crystals, gels, and amyloids: intracellular and extracellular phenotypes at the crossroads of immunoglobulin physicochemical property and cell physiology.A residue-specific shift in stability and amyloidogenicity of antibody variable domains.
P2860
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P2860
Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL).
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@ast
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@en
Immunoglobulin light chain variable
@nl
type
label
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@ast
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@en
Immunoglobulin light chain variable
@nl
prefLabel
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@ast
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@en
Immunoglobulin light chain variable
@nl
P2093
P1433
P1476
Immunoglobulin light chain var ...... n-associated amyloidosis (AL).
@en
P2093
Cristine Allmer
Rafael Fonseca
Roshini S Abraham
Susan M Geyer
Tammy L Price-Troska
P304
P356
10.1182/BLOOD-2002-09-2707
P407
P577
2002-12-19T00:00:00Z